Vitamin B1 10% w/v Solution for Injection for Cattle and Sheep 50ml.
Qualitative and quantitative composition
Each ml contains:
| Active Substance(s) | %w/v |
| Thiamine Hydrochloride | 10.0 |
| Excipient(s) | |
| Benzyl Alcohol (as preservative) | 1.5 |
|
|
For a full list of excipients, see Pharmaceutical Particulars
Pharmaceutical form
Solution for injection.
A clear, colourless to greenish-yellow liquid.
Clinical particulars
Target species
Cattle and Sheep.
Indications for use
For the treatment of cerebrocortical necrosis in cattle and sheep and as an adjunct in metabolic disorders of cattle.
Contra-indications
Do not use in cases of known hypersensitivity to the active ingredient.
Special warnings for each target species
Not applicable.
Special precautions for use
Special precautions for use in animals
Intravenous injections should be given slowly.
Observe aseptic techniques.
Special precautions to be taken by the person administering the veterinary product to animals
Care should be taken to avoid accidental self-injection. In the event of accidental self-injection, consult medical advice immediately and show the doctor this label. Wash hands after use.
Adverse reactions
Adverse effects are not anticipated following administration of thiamine.
Use during pregnancy, lactation or lay
It is not anticipated that the use of Vitamin B1 Injection will lead to any undesirable effects during Pregnancy and/or Lactation.
Interactions
None Known.
Amounts to be administered and administration route
By intramuscular or slow intravenous injections.
Dosage: 2.5 - 5ml per 50 kg bodyweight. Repeat every 3 hours for up to a total of 5 doses.
Overdose
Thiamine is very soluble in water and excess is excreted in the urine as a pyrimidine or as unchanged material. Tolerance studies have been carried out at twice the maximum recommended dose and the product was well tolerated.
Withdrawal periods
Meat-Zero days
Milk-Zero hours
Pharmacological particulars
Pharmacotherapeutic group: Vitamins, Vitamin B1, plain and in combination with vitamins B6 and B12, Vitamin B1, plain. ATC vet code: QA11DAO1.
Vitamin B1, also known as thiamine and as aneurine, is a water soluble vitamin. Aneurine is converted in the body to aneurine pyrophosphate (cocarboxylate) which acts as a coenzyme for several decarboxylating enzyme systems, the most important of which is decarboxylase. The enzyme is necessary for the decarboxylation of pyruvic acid, an intermediate stage in carbohydrate build-up or breakdown. When carbohydrates are a major source of energy the body requirements of aneurine increase. Deficiencies affect the nervous and gastrointestinal systems and skin.
Tissues dependent on glucose or lactate-pyruvate for energy such as the brain and heart are particularly compromised in thiamine deficiency. Thiamine deficiency may be primary, due to deficiency in the diet, or secondary, because of destruction of the vitamin in the diet by thiaminase. The principal cause of thiamine deficiency is the presence of thiamine-destroying agents which are widely distributed in nature, and produced by rumen microflora. Growing sheep are particularly susceptible, and outbreaks of cerebrocortical necrosis have been associated with sulphur in the diet.
Pharmaceutical particulars
Major incompatibilities
None known.
Shelf life
Shelf-life of the veterinary medicinal product as packaged for sale: 3 years.
Shelf-life after first opening the immediate packaging: 28 days.
Special precautions for storage
Do not store above 25°C.
Protect from light.
Once broached, use vial within 28 days. Discard unused material.
Immediate packaging
50 ml amber type II glass vial with a red bromobutyl rubber bung and plain aluminium cap.
Disposal
Any unused product or waste material should be disposed of in accordance with national requirements.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
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We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a valid signed and dated prescription.
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Please ring us on 01833 641112 for more information.
Refrigerated Items
Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
