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Vitamin B1 10% w/v Solution for Injection 50ml

BIMEDA

Item no: VITAMINB1
 
Vitamin B1 10% w/v Solution for Injection 50ml. For the treatment of cerebrocortical necrosis in cattle and sheep and as an adjunct in metabolic disorders of cattle.
Prescription Medicine
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£57.69
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Vitamin B1 10% w/v Solution for Injection for Cattle and Sheep 50ml.

Qualitative and quantitative composition

Each ml contains:

 

Active Substance(s)

%w/v

Thiamine Hydrochloride

10.0

Excipient(s)

 

Benzyl Alcohol (as preservative)

1.5

 

For a full list of excipients, see Pharmaceutical Particulars

 
Pharmaceutical form

Solution for injection.

A clear, colourless to greenish-yellow liquid.

Clinical particulars

Target species

Cattle and Sheep.

Indications for use

For the treatment of cerebrocortical necrosis in cattle and sheep and as an adjunct in metabolic disorders of cattle.

Contra-indications

Do not use in cases of known hypersensitivity to the active ingredient.

Special warnings for each target species

Not applicable.

Special precautions for use

Special precautions for use in animals

Intravenous injections should be given slowly.

Observe aseptic techniques.

Special precautions to be taken by the person administering the veterinary product to animals

Care should be taken to avoid accidental self-injection. In the event of accidental self-injection, consult medical advice immediately and show the doctor this label. Wash hands after use.

Adverse reactions

Adverse effects are not anticipated following administration of thiamine.

Use during pregnancy, lactation or lay

It is not anticipated that the use of Vitamin B1 Injection will lead to any undesirable effects during Pregnancy and/or Lactation.

Interactions

None Known.

Amounts to be administered and administration route

By intramuscular or slow intravenous injections.

Dosage: 2.5 - 5ml per 50 kg bodyweight. Repeat every 3 hours for up to a total of 5 doses.

Overdose

Thiamine is very soluble in water and excess is excreted in the urine as a pyrimidine or as unchanged material. Tolerance studies have been carried out at twice the maximum recommended dose and the product was well tolerated.

Withdrawal periods

Meat-Zero days

Milk-Zero hours

Pharmacological particulars

Pharmacotherapeutic group: Vitamins, Vitamin B1, plain and in combination with vitamins B6 and B12, Vitamin B1, plain. ATC vet code: QA11DAO1.

Vitamin B1, also known as thiamine and as aneurine, is a water soluble vitamin. Aneurine is converted in the body to aneurine pyrophosphate (cocarboxylate) which acts as a coenzyme for several decarboxylating enzyme systems, the most important of which is decarboxylase. The enzyme is necessary for the decarboxylation of pyruvic acid, an intermediate stage in carbohydrate build-up or breakdown. When carbohydrates are a major source of energy the body requirements of aneurine increase. Deficiencies affect the nervous and gastrointestinal systems and skin.

Tissues dependent on glucose or lactate-pyruvate for energy such as the brain and heart are particularly compromised in thiamine deficiency. Thiamine deficiency may be primary, due to deficiency in the diet, or secondary, because of destruction of the vitamin in the diet by thiaminase. The principal cause of thiamine deficiency is the presence of thiamine-destroying agents which are widely distributed in nature, and produced by rumen microflora. Growing sheep are particularly susceptible, and outbreaks of cerebrocortical necrosis have been associated with sulphur in the diet.

Pharmaceutical particulars

Major incompatibilities

None known.

Shelf life

Shelf-life of the veterinary medicinal product as packaged for sale: 3 years.

Shelf-life after first opening the immediate packaging: 28 days.

Special precautions for storage

Do not store above 25°C.

Protect from light.

Once broached, use vial within 28 days. Discard unused material.

Immediate packaging

50 ml amber type II glass vial with a red bromobutyl rubber bung and plain aluminium cap.

Disposal

Any unused product or waste material should be disposed of in accordance with national requirements.

 

Shipping charges mainland UK zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250g £2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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