Horses and ponies
Indications for use
Active immunisation of horses and ponies from 5 months of age for:
- Reduction of body temperature increase, coughing, inappetence, difficulty swallowing, and changes in demeanour in the acute stage of infection with Streptococcus equi.
- Reduction of number of abscesses within submandibular and retropharyngeal lymph nodes.
Onset of immunity: 2 weeks after the second vaccination dose.
Duration of immunity: 2 months after the second vaccination dose.
Special warnings for each target species
Vaccinate healthy animals only.
Effect of vaccination on further stages of the infection, rupture of developed lymph node abscesses, prevalence of subsequent carrier status, bastard strangles (metastatic abscessation), purpura haemorrhagica and myositis and recovery, is not known.
Efficacy has been demonstrated for the individual horse to reduce clinical signs of disease in the acute stage of the infection. Vaccinated horses can be infected and shed S. equi.
Special precautions for use in animals
No information is available on the use of the vaccine in seropositive animals, including those with maternally derived antibodies.
Biosecurity procedures to limit the risk of introduction and spread of S. equi infection in premises should be part of management tools.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician. An allergic reaction may occur. Treat symptomatically. Strangvac contains saponins, which have little toxicity for humans when ingested but have haemolytic effects when injected intravenously.
Adverse reactions
A transient increase in body temperature of up to 2.6°C may occur very commonly and last for one to five days following vaccination. Transient local tissue reactions are very commonly seen at the injection site, characterised by heat, pain and swelling (up to 5 cm diameter), and last for up to five days. Prevalence of injection site reactions are more pronounced after the second primary dose or re-vaccinations including increased swelling of up to 8 cm diameter. Ocular discharge is very commonly seen, which may be mucopurulent and present from both eyes for one to five days after vaccination. Loss of appetite and demeanour changes are common for up to one day. Anaphylactic-like reactions occur in very rare cases. Potential complications from vaccination and S. equi infection following challenge were not investigated.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Use during pregnancy and lactation
Pregnancy and lactation:
The safety of the veterinary medicinal product has not been established during pregnancy or lactation. The use of this vaccine is not recommended during pregnancy or lactation.
Fertility:
The safety and efficacy of the vaccine has not been established in breeding males. The vaccine should be used only according to the benefit-risk assessment by the responsible veterinarian.
Interactions
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
Amounts to be administered and administration route
Intramuscular use.
Shake the vial well before use. Avoid multiple vial broaching. Avoid introduction of contamination.
It is recommended that all horses and ponies in a stable are vaccinated.
Vaccination schedule:
Primary vaccination course:
Administer one dose (2 ml) by intramuscular injection, followed by a second dose (2 ml) four weeks later.
Revaccination:
In horses at high risk of S. equi infections it is recommended to repeat the primary vaccination regimen after two months.
Withdrawal periods
Zero days.
Pharmacological particulars
Pharmacotherapeutic group: immunologicals for Equidae, inactivated bacterial vaccines for horses.
ATCvet code: QI05AB01 – streptococcus.
The vaccine contains recombinant protein antigens derived from Streptococcus equi, which are not living and cannot spread to other animals. Strangvac stimulates active immunity against Streptococcus equi, the causative agent of strangles in horses. After vaccination, in addition to antibodies in the blood, local antibodies (IgG) can also be detected in secretions from the nasal passages. The immunogenicity of the Streptococcus equi antigens is enhanced by ISCOM (Immune Stimulating COMplex). Based on measured antibody titers immunological memory response was found in horses following repeated vaccination 6 months after primary vaccination. The role of the measured antibodies in the immune response relevant for the protection against strangles is not known.
Strangvac does not contain the DNA targets of diagnostic qPCR tests for Streptococcus equi or the A and C antigens used in the iELISA diagnostic test for exposure to Streptococcus equi.
Pharmaceutical particulars
Incompatibilities
Do not mix with any other veterinary medicinal product.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 2 years
Shelf life after first opening the immediate packaging: use immediately
Special precautions for storage
Store and transport refrigerated (2–8°C).
Do not freeze.
Keep the vial in the outer carton in order to protect from light.
Immediate packaging
Type I glass vial closed with a bromobutyl rubber stopper and sealed with a white aluminium crimp cap.
Package size: Cardboard box with 8 vials of 1 dose (2 ml).
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
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We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a valid signed and dated prescription.
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We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated Items
Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
