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Scabivax Forte Solution for Injection for sheep (50 doses)

Item no: SCABIVAXF
 
Prescription Medicine

Out of stock

Scabivax Forte Solution for Injection for sheep 50 Dose.

Qualitative and quantitative composition

Per dose of 0.02 ml:

Active ingredient: Orf virus 105.4 - 106.5 TCID50.


Excipients: For a full list of excipients, see section "Pharmaceutical particulars."

Pharmaceutical form

Solution for cutaneous administration.

Clinical particulars

Target species

Sheep, from one day of age.

Indications for use

For the active immunisation of sheep and lambs against Orf to reduce clinical signs and/or lesions of the disease. Immunity develops within 4-8 weeks of vaccination and is protective against severe signs of contagious pustular dermatitis for at least 12 months.

Contra-indications

The vaccine should not be used on farms or in flocks where Orf disease is not a problem.

Do not vaccinate ewes less than 7 weeks before lambing. Do not vaccinate pregnant ewes except at the recommended stage of pregnancy.

Special warnings for each target species

None.

Special precautions for use

Scabivax Forte is a live virus vaccine, and thus care must be taken to apply the vaccine only to the intended vaccination site and to not contaminate other sites such as mouth, feet, superficial wounds or abraded skin of the animal. Vaccinated lambs may transmit the disease to ewes' udders. Ewes that are vaccinated prior to lambing should not be moved to the proposed place of lambing until sufficient time has passed for the scabs to drop off (minimum of 7 weeks). Where indoor housing is practiced, routine cleansing and disinfection of the premises is an important aid in the control of Orf. In cases where vaccination of lambs cannot be delayed until turnout, veterinary advice should be sought as to how to minimise the risk of infection.

Ewes with unvaccinated lambs at foot are best to have their vaccination delayed until the lambs are weaned, except in case of emergency. Vaccinate these ewes as for pregnant ewes. For a period of up to 7 weeks after vaccination, or until the scabs resulting from the vaccine "take" have dropped totally, animals will be shedding virus infected scabs. During this time, vaccinated animals should not be:

•allowed access to lambing pens or pasture where ewes and their lambs will subsequently be grazed;

•allowed to come into contact with unvaccinated sheep and susceptible species;

•marketed, slaughtered or shorn.

Care must be taken not to contaminate the ground area with vaccine or used materials due to the persistence of Orf virus in the environment.

Do not vaccinate ewes or lambs during wet weather.

Vaccination of ewes before lambing will not provide protective immunity to the lambs via the colostrum. Therefore, if Orf disease is a problem in the lamb flock as well, the lambs should also be vaccinated to ensure protection throughout the entire flock.

Operator warnings:

Orf disease is caused by a virus which is communicable to man. The vaccine is capable of causing a skin infection in humans so should not be used by immuno-suppressed individuals. In the case of accidental self-administration (injection or scratch), ingestion or spillage onto the skin or into the eye, seek medical advice immediately and show the package insert or label to the physician. Rubber gloves should be worn when handling this product or dismantling the Applicator. Hands and arms should be washed after vaccination.

Adverse reactions

Effects other than those which characterise the vaccine "take" have not been observed.

Use during pregnancy, lactation or lay

No adverse effect has been recorded as a result of the use of this vaccine during pregnancy, at 7-8 weeks prior to lambing; do not use within 7 weeks of lambing. Do not use in other stages of pregnancy.

Lactating ewes can be vaccinated; ewes with lambs at foot should only be vaccinated at the recommended site.

Interactions

No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

Care should be taken to avoid treatment of the animals near the period of vaccination with substances or medicaments that might interfere with the "take" of this live vaccine.

Amounts to be administered and administration route

Dose: 0.02 ml administered by skin scarification.

This vaccine must be administered to sheep and lambs using an applicator, such as the Scabivax Forte Applicator, that dispenses a 0.02 ml dose of vaccine and prevents back flush. Refer to Section "Special precautions for use" for information on risks to the operator.

Prior to first vaccination and each subsequent vaccination session, and at the end of each vaccination session, the Applicator should be (re)sterilised. Do not use disinfectants to clean the Applicator as residues may harm the vaccine when next used.

When using the Scabivax Forte Applicator, place the vaccine bottle into the plastic sleeve supplied with the Applicator, when ready to commence vaccination. Ensure the Applicator is in an upright position, to avoid scratching the operator. Push the bottle, now inside the sleeve, firmly onto the draw off needle until it can go no further. Ensure the needle punctures the centre of the rubber circle on the top of the bottle. In order to prime the Applicator for vaccine application, ensure the Applicator is in the locked position. Holding the vaccinator so that it points to the ground, press down on the base of the vaccine bottle in a "pump like" action. Priming should take approximately 10 pumps. When the vaccine flows onto the scratcher prongs, the Applicator is primed and ready for use. The small drop of liquid, measured to a precise dose, is supported by the Applicator prongs until the product is applied. Prior to vaccination of each subsequent animal, the Applicator must be pumped once to recharge the Applicator prongs with a precise dose of vaccine.

Ewes that are vaccinated prior to lambing should not be moved to the proposed place of lambing until sufficient time has passed for the scabs to drop off (minimum of 7 weeks). Where indoor housing is practiced, routine cleansing and disinfection of the premises is an important aid in the control of Orf. In cases where vaccination of lambs cannot be delayed until turnout, veterinary advice should be sought as to how to minimise the risk of infection.

Site of administration:

Ewes: Pregnant ewes should be vaccinated behind the elbow or in the axilla (i.e. between the top of the foreleg and the chest wall), to prevent infection of the udder and subsequent transmission to lambs. Vaccinate ewes 7-8 weeks before lambing. Do not vaccinate ewes less than 7 weeks before lambing.


Ewes with unvaccinated lambs at foot are best to have their vaccination delayed until the lambs are weaned, except in case of emergency. Vaccinate these ewes as for pregnant ewes.

Lambs: Lambs may be vaccinated at any time from birth. Young (i.e. unweaned) lambs should be vaccinated in the axilla.

Method of administration:

Restrain the lamb or sheep over a rail or similar with the bare skin exposed. To apply the vaccine, place the Applicator prongs onto the skin and commence making a 4 to 5 cm scratch. The vaccine dose will be evenly deposited along the scratch. The Applicator must be held at an angle to the skin (approximately 45 degrees). Press firmly to ensure there is sufficient skin damage to enable an effective vaccination "take". The scratch should be just sufficient to break the top layer of the skin but not deep enough to draw blood.

As frequently as required, wipe the Applicator tip on a piece of cotton-wool or tissue to remove grease, dirt and wool collected from the sheep's skin, taking care not to contaminate the hands. It is advisable to have a plastic bag open and pinned up to receive used materials. Burn or sterilise used materials as soon as possible after use.

At the site of vaccination, erythema local to the line(s) of scarification are to be expected as the initial, observable effect, days 1-14 post-vaccination. Vesicles and pustules may then be observed, from approximately day 3-14 post-vaccination, and restricted to the site of scarification. Rupture of these vesicles and pustules, and scab formation, can be expected from about day 7 post-vaccination. These effects are expected in up to 100% of animals treated and are commonly referred to as vaccine "takes"; they indicate successful vaccination. In susceptible animals (those at risk of Orf virus infection) the aim is to obtain a "take" in each animal vaccinated. Animals which are immune because of previous vaccination or infection may not develop these "takes".

It is strongly recommended that the effectiveness of vaccination be assessed by examination of a selected group of sheep and/or lambs, one week to 10 days after vaccination. A more or less continuous line of pustules should be visible along the track of the scratch made on the skin. The pustules progress to form scabs which gradually dry and fall off by 7 weeks after vaccination.

Susceptible sheep or lambs must "take" in order to become immunised against Orf disease. Failure to "take" may be due to poor vaccination technique, improper handling of the vaccine resulting in loss of potency, or because the sheep are already immune. Revaccination once should be considered where a "take" has not occurred.

Overdose

Secondary bacterial infection may be observed in association with the scarification wounds; specific therapy may be required.

Withdrawal periods

Zero days.

Pharmacological particulars

Immunological properties

Live viral vaccine. ATC vet code QI04AD01.

To stimulate active immunity against contagious pustular dermatitis (Orf) virus.

Pharmaceutical particulars

Excipients

Patent Blue V (E 131), HEPES buffer, Sodium hydrogen carbonate, Eagles Minimum essential medium with non-essential amino acid, Foetal bovine serum, NZ Amine type B, Sucrose, Gelatin, Glutamine, Glycerol and Water for injections.

Major incompatibilities

Do not mix with any other veterinary medicinal product. Do not administer or treat with surface-active agents such as antiseptics, sprays or dips within 7 days before or after administration of the vaccine. Do not administer corticosteroids or other immunosuppressive drugs within 28 days before or after administration of the vaccine.

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale 2 years.

Shelf life after first opening the immediate packaging: 8 hours.

This product does not contain preservative.

Special precautions for storage

Store and transport refrigerated (2°C - 8°C). Protect from light.

Immediate packaging

Cardboard box with 1 glass bottle containing 50 doses of liquid vaccine, sealed with a rubber stopper and aluminium cap. The Scabivax Forte Applicator is supplied separately.

Can I vaccinate if lesions have appeared Please speak to your veterinary surgeon

 

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

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Refrigerated Items

  • Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
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We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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