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ReproCyc PRRS EU lyophilisate & solvent for suspension for Pigs

Boehringer

Item no: REPROCYC
 
Prescription Medicine Despatched with Woolcool Refrigerated Packaging, please see our delivery page for more information
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  • 100ml (50 Dose)
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ReproCyc PRRS EU lyophilisate and solvent for suspension for injection for pigs.

Uses
For active immunisation of breeding females from farms affected with European (genotype 1) Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) to reduce the duration of viraemia, the proportion of viraemic gilts/sows and viral loads in blood after exposure to PRRSV as shown under experimental conditions.

Onset of immunity : 5 weeks
Duration of immunity :17 weeks

Vaccination of breeding females according to the recommended schedule described below reduces the negative reproductive disorders associated with PRRSV.

Under experimental challenge conditions a reduction in transplacental virus transmission after challenge was additionally demonstrated. In piglets from vaccinated sows, a reduction in the negative impact of PRRS virus infection (mortality, clinical signs and weight gain) was also demonstrated during the first 20 days of life.

Dosage and administration
Single intramuscular injection of one dose (2 ml), irrespective of body weight.

For reconstitution, transfer the entire content of the solvent vial to the vial containing the lyophilisate and reconstitute the lyophilisate as follows: 10 doses in 20 ml, 50 doses in 100 ml and 100 doses in 200 ml of the solvent.

Ensure that the lyophilisate is completely reconstituted before use.
Avoid introduction of contamination during use.
Use sterile equipment.
Avoid multiple broaching, for example by using automatic injectors.

Regime of vaccination:
Gilts: for protection against PRRSV during pregnancy vaccination is recommended before integration into the sow herd between 2 and 5 weeks prior to breeding. Gilts can then be subjected to the same vaccination programme as the sow herd.

Sows: mass vaccination is recommended in a whole herd programme, in which all the pregnant and non-pregnant sows in the herd are vaccinated every three to four months.

Contra-indications, warnings, etc
Do not use in case of hypersensitivity to the active substance or to any of the excipients.

Do not use in boars producing semen for naïve herds, as PRRSV can be shed in semen.

Do not use in PRRS naïve herds in which the presence of PRRSV has not been established using reliable diagnostic methods.
Precautions should be taken to avoid the transfer of the vaccine virus within the herd, e.g. from positive animals to naïve animals.

Special precautions for use in animals
Vaccinate only clinically healthy animals.
The vaccine strain may spread up to 5 weeks after vaccination to unvaccinated animals in contact but without any clinical consequence. Vaccinated animals may excrete the vaccine strain by faecal excretion. The potential excretion of the vaccine strain in the urine of vaccinated animals has not been investigated.

The vaccine strain has been detected in new-born piglets (blood, lung samples) when vaccinating naïve gilts during last third of gestation but without any clinical consequence.

Care should be taken to avoid spread of vaccine virus from vaccinated animals to unvaccinated animals that should remain free from PRRSV.

It is advised to vaccinate all breeding females within a herd. Newly introduced PRRSV-naïve females (e.g. replacement females from PRRSV-negative herds) should be vaccinated prior to pregnancy.
For optimal PRRSV control programme, all animals in a herd should be vaccinated.

A transient increase in body temperature (up to 2°C above the physiological range) commonly occurs up to 5 days post-vaccination.

Temperatures return to the normal range without additional treatment, 1 to 4 days after the maximum temperature increase is observed.

Commonly, reduced appetite may be observed after vaccination.
Uncommonly, recumbency and accelerated breathing can be observed on the day of vaccination. These signs disappear spontaneously without any treatment.

Commonly, very minimal swelling or redness of the skin at the injection site may be observed. These reactions (up to 8cm but typically < 2 cm in size) are transient and subside within a short time (maximum of 5 days but typically less than 2 days) without treatment.

Can be used during pregnancy and lactation.
PRRSV naïve gilts should not be vaccinated during pregnancy.
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
No adverse events other than those listed above for a single dose were observed following a 10-fold overdose administration.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case adverse reactions develop following accidental self-injection, seek medical advice and show the package leaflet or the label to the physician.

Withdrawal period
Zero days.

Pharmaceutical precautions
Do not mix with any other veterinary medicinal product except solvent supplied for use with the veterinary medicinal product.
For animal treatment only. To be supplied only on veterinary prescription. Keep out of the sight and reach of children.
Store and transport refrigerated (2 °C – 8 °C). Do not freeze. Protect from light.

Shelf life of the vaccine lyophilisate as packaged for sale: 15 months
Shelf life of the solvent as packaged for sale: 3 years
Shelf life after reconstitution according to directions: 4 hours
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Legal category
Legal category: POM-V

Packaging quantities
Lyophilisate: Type I amber glass vials with bromobutyl rubber stopper and aluminium seal.
Solvent: High density polyethylene (HDPE) vials with a bromo- or chlorobutyl rubber stopper and aluminium seal.
1 lyophilisate vial of 20 ml (10 doses), 100 ml (50 doses) or 200 ml (100 doses) and 1 solvent vial of 20 ml, 100 ml or 200 ml packed in one cardboard box. 12 or 25 lyophilisate vials of 20 ml (10 doses), 100 ml (50 doses) or 200 ml (100 doses) packed in a separate cardboard box. 12 or 25 solvent vials of 20 ml, 100 ml or 200 ml packed in a separate cardboard box. Not all package sizes may be marketed.

Further information
The vaccine is designed to stimulate the development of an immune response in pigs to Porcine Reproductive and Respiratory Syndrome virus.

 

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.

Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout. 

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Estimated "Usually shipped in" information is shown against most products

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We no longer send goods outside of the UK.

Prescription Items

Prescription items will be sent on receipt of a legally valid signed and dated prescription.

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We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

  • Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
Wool cool keeps pharmaceutical products at fridge-like, ambient, or even freezing temperatures for up to 72 hours, and possibly longer depending on the contents and use of ice packs.
Important Delivery Information:
  • Receipt Required: Someone must be available to receive the delivery. Woolcool packaging is designed for temperature-controlled goods, so parcels cannot be left unattended.
  • Immediate Refrigeration: Upon receipt, refrigerate the contents immediately to ensure your food or medicine remains at the correct temperature.
  • Failed Delivery Attempts: We are not responsible for the cost of replacements if a delivery attempt fails due to the absence of someone to receive it.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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