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Porcilis Coli Clos Suspension for injection for pigs 50ml


Item no: PORCCC
Porcilis Coli Clos Suspension for injection for pigs 50ml, 25 Dose. For the passive immunisation of progeny by active immunisation of sows and gilts to reduce mortality and clinical signs during the first days of life, caused by some E. coli strains
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Porcilis Coli Clos Suspension for injection for pigs 50ml, 25 Dose.

Qualitative and quantitative composition

Each dose of 2 ml contains:

Active substances:

Escherichia coli components:


- F4ab fimbrial adhesin


9.7 log2 Ab titre1

- F4ac fimbrial adhesin


7.8 log2 Ab titre1

- F5 fimbrial adhesin


7.4 log2 Ab titre1

- F6 fimbrial adhesin


7.6 log2 Ab titre1

- LT toxoid


12.0 log2 Ab titre 1

Clostridium perfringens component:


- Type C (strain 578) beta toxoid


20 IU2

1 Mean antibody titre (Ab) obtained after vaccination of mice with a 1/20 or 1/20 sow dose

2 International units of beta antitoxin according to Ph.Eur.


dl-alpha-tocopheryl acetate 150 mg.

For full list of excipients, see section "Pharmaceutical Particulars".


Pharmaceutical form

Suspension for injection. Aqueous, white to nearly white.


Clinical particulars

Target species

Pigs (sows and gilts).

Indications for use

For the passive immunisation of progeny by active immunisation of sows and gilts to reduce mortality and clinical signs during the first days of life, caused by those E. coli strains, which express the adhesins F4ab (K88ab), F4ac (K88ac), F5 (K99) or F6 (987P) and caused by C. perfringens type C.



Special warnings for each target species


Special precautions for use

Special precautions for use in animals

Vaccinate only healthy animals. Protection of piglets is achieved by colostrum intake. Therefore, care should be taken to ensure that each piglet ingests a sufficient quantity of colostrum.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.

Adverse reactions

An increase in body temperature up to 2°C may be observed on the day of vaccination. Reduced activity and lack of appetite on the day of vaccination commonly occurs and/or a sometimes painful and hard swelling up to 10 cm diameter for up to 25 days may be observed at the site of injection.

Use during pregnancy, lactation or lay

Can be used during pregnancy.


No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

Amounts to be administered and administration route

Intramuscular injection of 1 dose (2 ml) of vaccine per animal in the neck in the area behind the ear.

Vaccination scheme:

Primary vaccination: Sows/gilts which have not yet been vaccinated with the product are given a primary injection 6 to 8 weeks before the expected date of farrowing and a second injection 4 weeks later.

Revaccination: A single revaccination is carried out 2 to 4 weeks before the expected date of farrowing.

Before use allow the vaccine to reach room temperature. Shake vigorously before use and at intervals during use.


A slight redness and/or roughness may transiently occur after a double dose vaccination. No adverse reactions other than those mentioned in section "Adverse reactions" have been observed.

Withdrawal periods

Zero days.


Pharmacological particulars

Immunological properties

Pharmacotherapeutic group: inactivated bacterial vaccine. ATC vet code: QI09AB08.

To stimulate active immunity in order to provide passive immunity to the progeny against enterotoxicosis caused by E. coli expressing fimbrial adhesins F4ab (K88ab), F4ac (K88ac), F5 (K99), F6 (987P) and against (necrotic) enteritis caused by C. perfringens type C. Vaccination results in an antibody response with neutralizing activity against LT toxin.


Pharmaceutical particulars


Sodium chloride, Potassium chloride, Disodium hydrogen phosphate, Potassium dihydrogenphosphate, Simethicone, Polysorbate 80 and Water for injections.

Major incompatibilities

Do not mix with any other veterinary medicinal product.

Shelf life

Shelf life of the veterinary medicinal product as packaged for sale: 2 years.

Shelf life after first opening the vial: 10 hours.

Special precautions for storage

Store in a refrigerator (between +2°C and + 8°C). Protect from light. Do not freeze.

Immediate packaging

Cardboard box with PET vial of 20 ml, 50 ml, 100 ml, 200 ml or 250 ml.

Cardboard box with type I glass vial of 20 ml, 50 ml, 100 ml or 250 ml.

The vials are closed with a halogenobutyl rubber stopper and sealed with an aluminium cap.

Not all pack sizes may be marketed.


Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Shipping charges mainland UK zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250g £2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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