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Naxcel 200 mg/ml Suspension Injection for Cattle 100ml


Naxcel 200 mg/ml Suspension Injection for Cattle 100ml. For use in cattle for the treatment of acute interdigital necrobacillosis, also known as Panaritium or foot rot (foul in the foot).
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Naxcel 200 mg/ml Suspension for Injection for Cattle.


Naxcel 200 mg/ml Suspension for Injection for Cattle is an opaque white to light brown suspension for injection. A one ml dose contains 200 mg ceftiofur (as ceftiofur crystalline free acid).


For use in cattle for the treatment of acute interdigital necrobacillosis, also known as Panaritium or foot rot (foul in the foot).

For use in cattle for the treatment of acute post-partum (puerperal) metritis, in cases where treatment with another antimicrobial has failed.

Dosage and administration

A single subcutaneous injection of 6.6 mg ceftiofur/kg bodyweight (equivalent to 1 ml of Naxcel per 30 kg bodyweight) administered at the base of the ear.

To ensure a correct dosage, bodyweight should be accurately determined to avoid under-dosing.

It is recommended to limit injection volumes to a maximum of 30 ml per injection site.

Shake the bottle vigorously for 30 seconds, or until all visual settlement has been resuspended.

Base of the ear administration:

•Administer in the posterior part of the ear base (see Figure 1).

•Hold the syringe and insert the needle behind the animal's ear so the needle and syringe point in the direction of an imaginary line that would pass through the head toward the animal's opposite eye (see Figure 2).

•Take appropriate precautions to avoid intra-arterial or intravenous injection, such as appropriate restraint of the animal (chute or head restraint for example) and using appropriate needles (1 inch (2.54 cm) long, 16 gauge).

If clinical signs have not improved 48 hours after treatment, the diagnosis and treatment of the condition should be re-evaluated.

Fig. 1 Injection location for the subcutaneous administration of Naxcel at the posterior aspect of the ear where it attaches to the head (base of ear)

Fig. 2 Subcutaneous administration of Naxcel at the posterior aspect of the ear where it attaches to the head (base of ear). Diagram of the head showing the direction for the base of the ear injections administered toward the animal's opposite eye

Naxel Cattle Picture 2013

Pfizer - Naxcel Cattle picture 1

Contra-indications, warnings, etc

Do not use in cases of hypersensitivity to ceftiofur or other beta-lactam antibiotics, or to any of the excipients.

Do not use as prophylaxis in cases of retained placenta.

For systemically administered broad spectrum cephalosporins (3rd and 4th generation, such as ceftiofur), it should be reflected that these are to be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other antimicrobials. Increased use, including use of the product deviating from the instructions given in the SPC/datasheet, may increase the prevalence of bacteria resistant to ceftiofur. Official, national and regional antimicrobial policies should be taken into account when the product is used.

Whenever possible, cephalosporins should only be used based on susceptibility testing. When considering the treatment strategy, it is appropriate to consider improvement of the herd management practice and use supporting treatment with suitable local products (e.g. disinfectants).

Visible swellings have been noted at the injection site in about two thirds of treated animals, two days after injection in field conditions. These reactions will resolve within a maximum of 23 days. Injection site swellings may result in mild to moderate pain in some animals in the initial days following injection.

In very rare cases (i.e. in less than 1-10 out of 10000 animals), sudden death has been reported following administration of the product. In such cases, death has been attributed to intra-vascular administration of the product or anaphylaxis.

In cattle, although Naxcel has not been specifically tested for overdoses, no signs of systemic toxicity related to ceftiofur have been observed following 55 mg/kg parenteral daily overdoses of ceftiofur sodium for five days.

Operator Warnings

Penicillins and cephalosporins such as ceftiofur may cause hypersensitivity in people and in animals following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross reactions to cephalosporins and vice versa. Allergic reactions to these substances may occasionally be serious.

People with known hypersensitivity to penicillins and cephalosporins should avoid contact with this veterinary medicinal product.

Avoid contact with skin or eyes. In the event of contact, wash with clean water. If you develop symptoms following exposure such as a skin rash or persistent eye irritation, you should seek medical advice and show the package leaflet or label to the physician. Swelling of the face, lips or eyes or difficulty with breathing are serious reactions and require urgent medical attention.

Withdrawal period

Meat and offal: 9 days.

Milk: zero days.

It is essential that Naxcel is only administered subcutaneously at the base of ear location in non-edible tissue, as described in the Dosage & Administration section, in order to comply with the meat withdrawal period.

Pharmaceutical precautions

Do not store above 25°C.

Shelf-life after first broaching the vial: 28 days.

In the absence of compatibility studies, Naxcel must not be mixed with other veterinary medicinal products.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

For animal treatment only.

Keep out of the reach and sight of children.

Legal category


Packaging Quantities

Cardboard box containing one glass vial of 100 ml.

Shipping charges mainland UK zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250g £2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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