Lincocin Sterile Solution for Injecton
A clear colourless sterile solution for injection. Each 1 ml contains lincomycin 100 mg (as lincomycin hydrochloride), plus 9 mg benzyl alcohol as a preservative.
Dogs and cats
For the treatment of infections caused by lincomycin susceptible Gram-positive organisms, particularly streptococci and staphylococci, and certain anaerobic bacteria (e.g. Bacteroides, Fusobacterium spp).
Tonsillitis, laryngitis and other upper respiratory tract infections
Lincocin Sterile Solution has proved effective against most causal organisms.
Abscesses, infected wounds and purulent dermatitis
Lincocin Sterile Solution has proved useful in clearing dermal infection since it readily penetrates tissues and maintains its action in the presence of purulent material.
Lincocin Sterile Solution has been used successfully to combat septicaemic conditions caused by organisms sensitive to lincomycin.
For the treatment of infections caused by lincomycin susceptible Gram-positive organisms (e.g. staphylococci, streptococci), certain Gram-negative anaerobic organisms (e.g. Serpulina (Treponema) hyodysenteriae, Bacteroides, Fusobacterium spp.), and Mycoplasma spp.
Lincocin Sterile Solution has been found to be effective in the treatment of swine dysentery. Lincocin Sterile Solution may be used in the inappetant pig when 1–2 injections with a 24-hour interval given intramuscularly at a dose of 10 mg/kg will normally be adequate to return the appetite. Follow-up treatment should be provided either in feed using Lincocin Premix or via the drinking water using Lincocin Soluble Powder.
Enzootic or mycoplasmal pneumonia
Lincocin Sterile Solution has antimycoplasmal activity, and will provide an effective aid in the treatment of the primary infective organisms and the secondary Gram-positive pathogens.
Septic arthritis, foot abscesses
Where these conditions are caused by staphylococci, streptococci, erysipelothrix and mycoplasma sensitive to lincomycin, this antibiotic provides useful treatment by virtue of its ability to penetrate relatively avascular tissue (e.g. joints) and remain active in the presence of purulent material.
Dosage and administration
Dogs and cats
Intramuscularly: 22 mg/kg of body weight (given by 1 ml per 4.5 kg bwt) once daily or 11 mg/kg (given by 1 ml per 9 kg bodyweight) every 12 hours. Intravenously: 11–22 mg/kg of bodyweight (given by 1 ml per 9–4.5 kg bwt) one or two times per day by slow intravenous injection.
Intramuscularly: 4.5–11 mg/kg of body weight (given by 1 ml per 22–9 kg bwt) once daily for a maximum of 3 days.
When injecting large volumes, a maximum of 10 mls per injection site should be administered. It is recommended that no more than two injections per day are given. At the lowest dose rate of 4.5 mg/kg, the maximum recommended weight of animal for treatment is 445 kg and at the higher dose rate of 11 mg/kg, the maximum weight of animal for treatment will be 180 kg.
Practice aseptic injection techniques.
Contra-indications, warnings, etc
Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption 3 days after last treatment. The intramuscular administration of Lincocin Sterile Solution to pigs at higher levels than recommended may result in diarrhoea and loose stools. This antibiotic is not effective against E.coli, Salmonella spp, Enterococcus faecalis or yeasts. Not to be used in animals hypersensitive to lincosamides.
Clinical antangonism may exist between lincomycin and erythromycin and concurrent use is therefore not recommended.
The use of Lincocin Sterile Solution is not recommended in species other than the cat, dog and pig. Do not administer to rabbits, hamsters, guinea pigs, chinchillas, horses or ruminants as this could result in severe gastro-intestinal disturbance.
Lincocin Sterile Solution should not be given to animals with a known pre-existing monilial infection.
When the intravenous route is to be used in the dog or cat, administration must be slow.
Avoid contact with the product. In case of accidental eye or skin contact, wash off the affected area thoroughly with water.
For animal treatment only.
Do not store above 25°C. Do not freeze. Avoid the introduction of contamination during use. Discard contents within 21 days of first use. Keep out of reach of children.
Lincocin Sterile Solution is supplied in a 100 ml multidose vial.