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Kexxtone 32.4g Continuous-Release Intraruminal Device

Eli Lilly

For the reduction in the incidence of ketosis in the peri-parturient dairy cow/heifer which is expected to develop ketosis.
Prescription Medicine
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Continuous-release intraruminal device containing Monensin 32.4 g (equivalent to 35.2 g monensin sodium).

Product Description

A cylindrical orange polypropylene intraruminal device uniquely identified with a number, fitted with wings, consisting of a core which presents as a stack of 12 subunits each containing 2.7 g monensin (equivalent to 2.9 g monensin sodium).


For the reduction in the incidence of ketosis in the peri-parturient dairy cow/heifer which is expected to develop ketosis.

Dosage and administration

Intraruminal use.

A single intraruminal device is to be administered to a dairy cow/heifer 3-4 weeks prior to expected calving, using the Kexxtone administration tool.

Kexxtone delivers an approximate average dose of 335 mg of monensin per day for approximately 95 days. Adequate animal restraint is required to properly administer this intraruminal device. Such restraint must limit forward/backward motion and allow the animal's head to be held in the forward extended position and without pressure on the neck to prevent choking.

1. Each intraruminal device has an individual number along the device body. This should be recorded with the corresponding animal identification number so that, should an intraruminal device be regurgitated, the animal can be identified.

2. Fold wings down along the intraruminal device body and insert the device into the Kexxtone administration tool, orifice end first.

3. Restrain the animal with its head and neck stretched forward. Grasp the animal with one hand in the corner of the animal's mouth. Introduce the administration tool into the mouth avoiding the front teeth. In order to avoid trauma and damage to the pharynx and oesophagus, do not use excessive force.

4. Insert the administration tool past the base of the tongue making sure to avoid the molar teeth. As the animal swallows, the administration tool will move easily over the base of the tongue. DO NOT USE EXCESSIVE FORCE. If resistance is encountered, withdraw the tool slightly and repeat the procedure.

5. Be sure the head of the administration tool is past the base of the tongue.When the animal swallows, eject the intraruminal device from the administration tool. In the event of early regurgitation, identify the animal by matching the animal ID number with the number on the intraruminal device and re-administer an undamaged intraruminal device.

Contra-indications, warnings, etc

Do not use in animals weighing less than 300 kg bodyweight.

Special precautions

Hold treated cattle in a confined area for 1 hour after administration to observe for failure to swallow or regurgitation. If this occurs re-administer the intraruminal device if undamaged. If damaged, administer a new intraruminal device. Recheck cattle for up to 4 days after dosing to observe for signs of an intraruminal device lodging in the oesophagus. Signs of lodging may include bloat which may be followed by coughing, drooling, inappetence and unthriftiness.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

Exposure to the active substance may elicit an allergic response in susceptible individuals. People with known hypersensitivity to monensin or any of the excipients should avoid contact with the veterinary medicinal product.

Do not eat, drink or smoke when handling the veterinary medicinal product.

Use gloves when handling an intraruminal device, including during retrieval of a regurgitated intraruminal device.

Remove gloves and wash hands and exposed skin after handling intraruminal devices.

Other precautions

Do not allow dogs, horses, other equines or guinea fowl access to formulations containing monensin. Consumption of intraruminal device contents can be fatal in these species.

Withdrawal Period

Meat and offal: Zero days

Milk: Zero days

Pharmaceutical precautions

For animal treatment only.For use in pregnant and lactating dairy cattle.

Keep out of reach and sight of children.

Any unused veterinary medicinal product, waste materials derived from such veterinary medicinal products or regurgitated intraruminal devices should be disposed of in accordance with local requirements.

Legal category


Packaging Quantities

Aluminium foil bag containing 1, 3 or 5 intraruminal device(s)

In outers of 20 x 1 Bolus or 8 x 5 Bolus

Not all pack sizes may be marketed.

Further information

Shelf life of the veterinary medicinal product as packaged for sale: 2 years

Shelf life after first opening the immediate packaging: 6 months

Pharmacotherapeutic group: Drugs for treatment of acetonemia, ATC vet code: QA16QA06

Accidental administration of more than one intraruminal device could result in some adverse reactions which are typical of monensin overdose, including decreased appetite, scouring and lethargy. These are generally transient. The highest tolerated dose is typically between 1 mg and 2 mg monensin/kg bodyweight/day.

Shipping charges mainland UK zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250g £2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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