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Ingelvac PRRSFLEX EU Suspension for Injection for Pigs


Ingelvac PRRSFLEX EU Lyophilisate and Solvent for Suspension for Injection for Pigs. For active immunisation of clinically healthy pigs at 17 days of age and older from farms affected with European (genotype 1) Porcine Reproductive and Respiratory S
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Ingelvac PRRSFLEX EU Lyophilisate and Solvent for Suspension for Injection for Pigs.

Target species:
Pigs (from 17 days of age until the end of fattening)

Indications for use, specifying the target species:
For active immunisation of clinically healthy pigs at 17 days of age and older from farms affected with European (genotype 1) Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) to reduce virus load in blood in seropositive animals under field conditions.

Under experimental challenge conditions in which only seronegative animals were included, it was demonstrated that vaccination reduces lung lesions, virus load in blood and lung tissues as well as negative effects of infection on daily weight gain. A significant reduction of the respiratory clinical signs could additionaly be demonstrated at the onset of immunity.

Onset of immunity:3 weeks
Duration of immunity:26 weeks

Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Do not use in breeding animals.
Do not use in PRRS naïve herds in which the presence of PRRSV has not been established
using reliable diagnostic methods.

Special warnings for each target species:
Precautions should be taken to avoid the transfer of the vaccine virus within the herd, e.g. from positive animals to naïve animals.
Do not use in boars producing semen for naïve herds, as PRRSV can be shed in semen.
Maternally derived antibodies have been shown to interfere with vaccine efficacy. In the presence of maternally derived antibodies, timing of initial vaccination of piglets should be planned accordingly.

Special precautions for use:
i)Special precautions for use in animals

Vaccinate only clinically healthy animals.

The vaccine strain may spread to unvaccinated animals in contact with vaccinated animals up to
3 weeks post vaccination. Vaccinated animals may excrete the vaccine strain by faecal excretion and in some cases by oral secretions.

Care should be taken to avoid spread of vaccine virus from vaccinated animals to unvaccinated animals that should remain free from PRRS virus.

For optimum PRRS control programme, all animals in a herd should be vaccinated. In the sow herd it is recommended to use a vaccine licensed for use in sows.

ii) Special precautions to be taken by the person administering the veterinary medicinal product to animals

In case adverse reactions develop following accidental self-injection, seek medical advice and show the package leaflet or the label to the physician.

Adverse reactions (frequency and seriousness):
Very commonly, slight transient increases (not greater than 1.5°C) in body temperature can be observed following vaccination. Temperatures return to normal without additional treatment,
1 to 3 days after the maximum temperature increase is observed.
Injection site reactions are uncommon. Transient minimal swelling or redness of the skin may be observed. These reactions disappear spontaneously without any additional treatment.

The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reactions during the course of one
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports).

Use during pregnancy, lactation and lay:
The safety of this veterinary medicinal product has not been established during pregnancy or lactation.

Interaction with other medicinal products and other forms of interaction:
No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

Amounts to be administered and administration route
Dosage and method of administration:
Single intramuscular injection of one dose (1 ml), irrespective of body weight.
For reconstitution, transfer the entire content of the solvent vial to the vial containing the lyophilisate and reconstitute the lyophilisate as follows: 10 doses in 10 ml, 50 doses in 50 ml, 100 doses in 100 ml and 250 doses in 250 ml of the solvent.
Ensure that the lyophilisate is completely reconstituted before use.
Avoid introduction of contamination during use.
Use sterile equipment.
Avoid multiple broaching, for example by using automatic injectors.

Overdose (symptoms, emergency procedures, antidotes), if necessary:
No additional negative effects have been observed following the administration of a 10-fold overdose in naïve piglets of two weeks of age with regard to systemic and local reactions.

Withdrawal period:
Zero days.

Pharmacotherapeutic group: Porcine Reproductive and Respiratory Syndrome Virus
ATCvet code: QI09AD03

The vaccine is designed to stimulate the development of an immune response in pigs to Porcine Reproductive and Respiratory Syndrome Virus.

List of excipients:
Potassium hydroxide
Glutamic acid
Potassium dihydrogen phosphate
Dipotassium phosphate
Sodium chloride

Phosphate buffered solution:
 Sodium chloride
 Potassium chloride
 Potassium dihydrogen phosphate
 Disodium hydrogen phosphate
 Water for injection

Do not mix with any other veterinary medicinal product except solvent supplied for use with the veterinary medicinal product.

Shelf life:
Shelf life of the vaccine lyophilisate as packaged for sale:   1 year
Shelf life of the solvent as packaged for sale:     3 years
Shelf life after reconstitution according to directions:    8 hours

Special precautions for storage:
Store and transport refrigerated (2 °C - 8  C).
Do not freeze.
Protect from light.

Nature and composition of immediate packaging:
Type I amber glass vials with bromobutyl rubber stopper and aluminium seal.

High density polyethylene (HDPE) vials with bromo- or chlorobutyl rubber stopper and aluminium seal.

1 lyophilisate vial of 10 ml (10 doses), 50 ml (50 doses), 100 ml (100 doses) or 250 ml (250 doses) and 1 solvent vial of 10 ml, 50 ml, 100 ml or 250 ml packed in one cardboard box.

12 or 25 lyophilisate vials of 10 ml (10 doses), 50 ml (50 doses), 100 ml (100 doses) or 250 ml
(250 doses) packed in a separate cardboard box.

12 or 25 solvent vials of 10 ml, 50 ml, 100 ml or 250 ml packed in a separate cardboard box.

Not all package sizes may be marketed.

Special precautions for the disposal of unused medicinal product or waste materials:
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.

Shipping charges mainland UK zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250g £2.99

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

Postage outside of the UK is from £4.50

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or Royal Mail with coolpacks unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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