*Images are for illustrative purposes only

Frontline Spray


  • Select Option
  • 250ml
Max 1 per customer
Adding to basket… The item has been added
Browse other products from the Frontline range

Frontline Spray: Effective Flea and Tick Treatment for Dogs and Cats

Frontline Spray provides a reliable solution for treating and preventing flea and tick infestations in both dogs and cats. Containing 0.25% w/v of the active ingredient Fipronil, this easy-to-apply cutaneous spray also controls biting lice. It is safe for use on puppies and kittens from as young as 2 days old. As an added benefit, the product can be integrated into treatment plans for Flea Allergy Dermatitis, as diagnosed by a veterinary surgeon.

Frontline Spray for Dogs Key Benefits

  • Effective Ectoparasiticide: Targets fleas, ticks, and biting lice.
  • Flea Allergy Dermatitis Support: Vet-approved for flea allergy dermatitis treatment.
  • Tick Control: One-month protection against ticks.
  • Safe for Puppies: Suitable for puppies as young as 2 days old.
  • Long-lasting Flea Protection: Active against fleas for up to 3 months.
  • Simple to Administer: Easy-to-use mechanical pump spray.
  • No Special Storage Conditions: Simple storage without temperature constraints.
  • Coat-Friendly: Adds gloss to the coat.

Frontline Spray for Cats Key Benefits

  • Broad-Spectrum Ectoparasiticide: Effective against fleas, ticks, and biting lice.
  • Flea Allergy Dermatitis Support: Vet-approved for treating flea allergy dermatitis.
  • Tick Protection: Offers up to one month of tick protection.
  • Safe for Kittens: Suitable for kittens from 2 days old.
  • Extended Flea Protection: Effective for up to 2 months against fleas.
  • User-Friendly: Mechanical pump spray for ease of application.
  • No Special Storage Requirements: Uncomplicated storage conditions.
  • Coat Benefits: Leaves fur glossy.

How to Use Frontline Spray for Dogs and Cats:


  1. Weigh Your Pet: Accurately weigh your pet to determine the correct dosage.
  2. Adjust Nozzle: Turn the nozzle of the spray bottle to the spray setting.
  3. Protective Gear: Wear PVC or nitrile gloves to avoid contact with the spray.


  1. Distance: Hold the spray bottle 10-20 cm away from your pet's body.
  2. Apply Against Hair Growth: Spray the solution against the lay of the hair, ensuring the entire coat is dampened.
  3. Ruffle the Coat: Particularly for long-haired pets, ruffle the coat to allow the product to penetrate to the skin level.
  4. Head Area: For treating the head or for young or nervous pets, spray onto a gloved hand and gently rub it into the coat.


  • Dogs and Cats: Depending on the length of the hair, apply 3 to 6 ml per kg of body weight. This translates to 2 to 4 pump applications for the 250 ml and 500 ml bottles.


  1. Natural Drying: Allow your pet to dry naturally. Do not towel dry.
  2. Ventilated Area: Make sure your pet dries in a well-ventilated room. Keep away from heat sources for at least 30 minutes after application.


  1. Handwashing: Dispose of gloves and wash your hands with soap and water.
  2. Pet Interaction: Do not handle the pet until the fur is completely dry.

Special Notes:

  • Retreatment: Do not reapply within 4 weeks.
  • Swimming: Dogs should not swim in water courses for 2 days after application.
  • Environmental Treatment: It's advisable to treat pet bedding and other areas with suitable insecticides such as Frontline Homegard for a more comprehensive flea and tick control strategy. 

Special Precautions

  • Do not use on sick or recovering animals.
  • Do not use in rabbits.
  • Do not overdose.
  • Do not use in pregnancy.
  • Do not mix with other direct-to-animal flea products.

Possible Side Effects:

  • If the animal licks the sprayed area, brief excess drooling may occur.

  • Very rarely, the following skin reactions have been reported:

  • Redness
  • Itching
  • Hair loss

In exceptional cases, the following symptoms have been noted:

  • Excess drooling
  • Temporary changes in behaviour like over-sensitivity or depression
  • Vomiting
  • Breathing difficulties

Note: Overdosing should be avoided to minimise the risk of side effects.


  • 250ml 
  • 500ml  

NB the 100ml bottle is discontinued from the manufacturer and no longer available.



Is frontline spray safe for puppies? Puppies and kittens from 2 days of age may be safely treated. -- Is Frontline spray for kittens under 8 weeks? Puppies and kittens from 2 days of age may be safely treated.

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.

Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

We no longer send goods outside of the UK.

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

Related Products