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Distocur Oral Suspension for Cattle & Sheep 5L

Trilanco

Item no: DISTOCUR
 

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Cattle and sheep: Treatment of infections caused
by the adult stage of Fasciola hepatica, sensitive to
oxyclozanide. Elimination of gravid tapeworm segments
(Moniezia spp)

ADVERSE REACTIONS
In very rare cases (less than 1 animal in 10,000 animals
treated, including isolated reports), a slight softening of
the faeces with animal showing increased frequency of
defecation and transient inappetence may appear
CONTRAINDICATIONS
Known hypersensitivity to the active substance or to any
of the excipients.
ROUTE OF ADMINISTRATION & DOSAGE
Oral use. Give as an oral drench. Shake the suspension
at least 5 times before use. To ensure administration of
a correct dose, body weight should be determined as
accurately as possible; accuracy of the dosing device
should be checked.
If animals are to be treated collectively rather than
individually, they should be grouped according to their
bodyweight and dosed accordingly, in order to avoid
under – or overdosing. Cattle: 10 mg oxyclozanide per kg
body weight (3 ml of product per 10 kg body weight).
For animals above 350 kg, dose is 3.5 g oxyclozanide per
animal, i.e. 103 ml of product. Sheep: 15 mg oxyclozanide
per kg body weight (corresponding to 4,4 ml of product
per 10 kg body weight). For animal above 45 kg, dose is
0,68 g oxyclozanide per animal, i.e. 20 ml of product.
WITHDRAWAL PERIOD
Cattle: Meat and offal: 13 days; Milk: 4.5 days (108 hours)
Sheep: Meat and offal:14 days; Milk: 7 days (168 hours)
SPECIAL WARNINGS
Special warnings for each target species
To date no resistance to oxyclozanide has been
reported. Use of the product should be based on local
(regional, farm) epidemiological information about
susceptibility of trematodes and recommendations
on how to limit further selection for resistance to
anthelmintics. At normal dose levels, oxyclozanide is not
active against immature flukes present in liver tissue.
Milking cattle, particularly high yielders, may show a
reduction in yield, occasionally of 5% or more, for about
48 hours after handling. The effect of this small loss may
be minimised by spreading herd dosing over a period of
about one week.

SPECIAL PRECAUTIONS FOR USE IN ANIMALS
To avoid damage to the pharyngeal region,
care should be taken when administering by dosing gun.
Adverse effects are occasionally enhanced in animals
suffering from severe liver damage and/or dehydration
at the time of dosing. Due regard must always be
given to the physical condition of animals undergoing
treatment, particularly those in advanced pregnancy
and/or under stress from adverse weather conditions,
poor nutrition, penning, handling, etc.
OTHER PRECAUTIONS
Oxyclozanide is toxic to dung fauna and aquatic
organisms. The risk can be reduced by avoiding too
frequent and repeated use of oxyclozanide in cattle.
Treated cattle must not graze near watercourses and
must not have access to water bodies for 5 days after
treatment.
USE DURING PREGNANCY & LACTATION
Laboratory studies during different phases of
reproduction have not produced any evidence of
teratogenic or foetotoxic effects, or negative effects
on fertility. Can be used during pregnancy and lactation.
However care should be taken when treating heavily
pregnant animals and animals under stress from
adverse weather conditions, poor nutrition, penning,
handling etc.
OVERDOSE
(symptoms, emergency procedures antidotes)
The adverse reactions observed at normal doses
are more pronounced at increased doses. At doses
of 50 mg/kg there is a risk of death. The effects of
oxyclozanide overdosage are dullness and some
loosening of faeces in sheep and possible diarrhoea,
inappetance and loss of weight in cattle. These effects
are very rarely enhanced in animals with severe liver
damage and/or dehydration at the time of dosing. On
veterinary prescription only

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