Pentosan Polysulphate Sodium is a semi-synthetic polymer with a mean molecular weight of 4000 Daltons, with anti-inflammatory activity, and modulating effects on cartilage and synovial metabolism and an affinity for cartilage. In addition, it has fibrinolytic, lipolytic and mild anti-coagulant activities. The therapeutic activity of the product arises from the action of Pentosan Polysulphate Sodium on the underlying pathological processes of osteoarthritis (disease modifying osteoarthritis drug or DMOAD) and results in analgesic and regenerative effects. Cartrophen Vet has been shown to produce equal improvement in the clinical signs of osteoarthritis when compared to the NSAID, carprofen.
Cartrophen Vet is indicated for the treatment of lameness and pain of osteoarthritis (non-infectious arthrosis) and related musculoskeletal disorders in the dog.
Dosage and administration
3 mg Pentosan Polysulphate Sodium/kg bodyweight on four occasions, with an interval of 5–7 days.
By aseptic subcutaneous injection only of 0.3 ml Cartrophen Vet/10 kg bodyweight. An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes.