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Bovivac S Suspension for Injection for Cattle 50ml



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Bovivac S Suspension for Injection for cattle.


Bovivac S is a suspension for injection containing inactivated cells of Salmonella dublin, strain S342/70 (1 x 109 cells/ml) and inactivated cells of Salmonella typhimurium, strain S341/70 (1 x 109 cells/ml). Bovivac S contains aluminium hydroxide as an adjuvant and thiomersal as a preservative.


For the active immunisation of cattle in order to induce serological and colostral antibody production against Salmonella dublin and Salmonella typhimurium and in the face of an outbreak to reduce Salmonella typhimurium infections when used under field conditions as part of an overall herd management programme. Bovivac S may also contribute to reducing S. typhimurium contamination of the environment.

Dosage and administration

Vaccination dosage

Calves up to 6 months of age – 2 ml

Adult cattle – 5 ml

Route and method of administration

Subcutaneous injection preferably in the loose skin on the side of the neck, observing aseptic precautions. Shake the vaccine bottle before use.

Primary vaccination course

Where diagnosis of salmonellosis caused by S. dublin and/or S. typhimurium has been confirmed, all at risk adult cattle, including lactating cows, dry cows, heifers, barren cows and in-contact bulls (but excluding any with overt clinical signs of salmonellosis), should receive two 5 ml injections separated by an interval of 21 days.

For pregnant cows, this primary vaccination course can be given irrespective of the reproductive status. Any pregnant cows that have not calved within 8 weeks of the second dose of vaccine should receive a further 5 ml dose of Bovivac S 3-4 weeks pre-calving.

Healthy calves from approximately 3 weeks of age may also be given a primary vaccination course. Calves should be given two 2 ml injections separated by an interval of 14 to 21 days.

Re-vaccination scheme

All cattle vaccinated with the primary vaccination course of Bovivac S should receive a 5 ml injection at least two weeks prior to each period of risk or at intervals of not more than 12 months thereafter.

As part of an overall herd management programme, for pregnant cattle, it is advised that for each subsequent pregnancy, in order to maintain a sufficient level of active immunisation to reduce S. dublin and S. typhimurium infections under field conditions, a single injection of 5 ml should be administered approximately 3-4 weeks before calving.

Advice on correct administration

The use of automatic vaccination equipment is recommended. Use a vaccinator with vented draw-off spike or similar device only.

The vaccine may be administered using a sterile needle and syringe, provided a fresh sterile needle is used each time the rubber cap is punctured, to avoid contamination of the remaining contents.

Contra-indications, warnings, etc

Swellings at the injection site may occur. Typically, these swellings may be warm when compared with the surrounding area for up to 5 days after vaccination, reach a maximum size within 1-6 days after vaccination and completely disappear or reduce to clinically insignificant reactions within 2-3 weeks after vaccination. In addition, swellings may be slightly painful on palpation for 1-2 days after vaccination, although this will not require veterinary intervention.

Occasional hypersensitivity reactions may occur.

If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.

All stock showing overt clinical signs of salmonellosis at the time of the initial vaccination programme should receive appropriate treatment and be fully vaccinated once they have recovered. Any unvaccinated stock must be managed separately to vaccinated stock, with no contact between the groups. Hygiene precautions must be instituted, where possible, to prevent transfer of infection from one group to another. All animals of a herd should be vaccinated.

Significant levels of immunity cannot be expected until two weeks after the second dose of the primary vaccination course.

The effect of maternally derived antibodies has not been studied, but it is likely that high levels of maternally derived antibodies may interfere with the development of active immunity in calves.

The efficacy of Bovivac S has been established in the field using the recommended programme of use.

Specific experimental data to quantify the duration of immunity, the effectiveness of a single dose re-vaccination or the degree of protection from colostral antibodies has not been generated.

When vaccinating animals, stress should be avoided, particularly during pregnancy.

The effect of Bovivac S administered around service/insemination has not been studied. Limited laboratory and field data suggest that vaccination with Bovivac S has no adverse effect on pregnancy and calving.

A small number of individuals may fail to respond to vaccination as a result of immunological incompetence or for some other reason. In the face of an outbreak of disease, it is therefore important to avoid vaccination of animals which have overt clinical salmonellosis or intercurrent disease or which have a poor nutritional status. Such animals must be isolated and treated as appropriate and then vaccinated upon clinical recovery.

No information is available on the safety and efficacy from concurrent use of this vaccine with any other. It is therefore recommended that no other vaccine should be administered within 14 days before or after vaccination with this product.

Do not mix with any other vaccine or immunological product.

Operator warnings

There are no special warnings applicable to people administering the vaccine.

Withdrawal period

Zero days.

For animal treatment only. Keep out of reach and sight of children.

Pharmaceutical precautions

Store in a refrigerator. Do not freeze. Protect from light.

Do not use after the expiry date stated on the label.

Once broached, use within 10 hours. Partially used containers must be discarded at the end of each day's operations.

Any unused product or waste materials should be disposed of in accordance with local requirements.

Legal category


Packaging Quantities

50 ml polyethylene multidose bottles.        

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.

Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

We no longer send goods outside of the UK.

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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