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Bovalto Respi 4 suspension for injection for cattle


Item no: BOVALTOR4
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£64.59 - £274.45
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Bovalto Respi 4 suspension for injection for cattle.

Target species

Indications for use, specifying the target species
For active immunisation of cattle in the absence of maternally derived antibodies against:
- parainfluenza 3 virus, to reduce virus excretion due to infection
- bovine respiratory syncytial virus, to reduce virus excretion due to infection
- bovine viral diarrhoea virus, to reduce virus excretion due to infection
- Mannheimia haemolytica serotype A1, to reduce clinical signs and lung lesions.
Onset of immunity (demonstrated by challenge):
3 weeks after primary vaccination
Duration of immunity (demonstrated by challenge):
6 months after primary vaccination


Special warnings for each target species

Special precautions for use in animals
Vaccinate only healthy animals.
Safety and efficacy studies were performed in sero-negative calves. The efficacy of the vaccination has not been demonstrated in presence of antibodies. The level of antibody response may be reduced by the presence of maternal antibodies. In the presence of maternal antibodies, timing of initial vaccination of calves should be planned accordingly.

Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case of accidental self- injection, seek medical advice immediately and show the package insert or label to the physician.

Adverse reactions (frequency and seriousness)
Following vaccination a localised swelling may be very commonly observed at the injection site. This swelling could reach up to 7 cm in diameter, and usually progressively reduces and disappears within 6 weeks after vaccination.

Commonly, there may be a transient slight increase in body temperature which was higher after the second injection (1.5°C at most) lasting up to 3 days after vaccination.

Anaphylactic-type reactions may very rarely occur after vaccination. In such cases, appropriate symptomatic treatment should be administered.

The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports)

Use during pregnancy, lactation or lay
Do not use during pregnancy and lactation.
Interaction with other medicinal products and other forms of interaction

No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product. A decision to use this vaccine before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.

Amounts to be administered and administration route
Dosage – 2 ml administered subcutaneously.
Warm before use to a temperature of 15 to 25 °C and shake the contents of the vial.

Primary vaccination
Calves can be vaccinated from 2 weeks of age.
Calves from non-immune dams: 2 injections 3 weeks apart from 2 weeks of age
Where the immune status of the dam is unknown, the vaccine scheme should be adapted at the discretion of the veterinarian.

Administer a single dose 6 months after completion of the primary vaccination scheme.
The revaccination was demonstrated by measurement of the serological response. The efficacy of the revaccination has not been assessed by challenge.

Overdose (symptoms, emergency procedures, antidotes), if necessary
No adverse effects other than those mentioned in the "Adverse Reactions" section were observed. Local reactions after subcutaneous administration of a double dose were larger (up to 10 cm in diameter) than after the recommended dose.

Withdrawal periods
Zero days.

Pharmacological particulars
Pharmacotherapeutic group: Immunologicals for cattle; inactivated viral and bacterial vaccines. The vaccine induces an active immunity against bovine respiratory syncytial virus, parainfluenza 3 virus, bovine viral diarrhoea virus and Mannheimia haemolytica.

Pharmaceutical particulars
List of excipients
Aluminium hydroxide, Thiomersal, Formaldehyde, Quillaja saponin (Quil A), Water of injection, Sodium chloride

Do not mix with any other veterinary medicinal product.
Shelf life
Shelf-life of the veterinary medicinal product as packaged for sale:
Glass vials: 2 years.
Plastic vials: 15 months.

Shelf-life after first opening the immediate packaging: 10 hours.
Special precautions for storage
Store and transport in a refrigerator (2 °C – 8 °C).
Do not freeze. Protect from light.

Nature and composition of immediate packaging
Translucent plastic bottle of 10, 50 or 100 mL with chlorobutyl elastomer closure (5, 25 or 50 doses)
Box of 1 bottle of 5 doses (10 ml), Box of 10 bottles of 5 doses (10 x 10 ml), Box of 1 bottle of 25 doses (50 ml), Box of 1 bottle of 50 doses (100 ml). Not all pack sizes may be marketed.

Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.

Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

We no longer send goods outside of the UK.

Prescription Items

Prescription items will be sent on receipt of a valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

Refrigerated items will be sent by carrier or express delivery at a cost of £7.50, with coolpacks, unless you pay for a premium for a refrigerated delivery. We will contact you prior to despatch for your instructions.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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