Zylexis Injection for Horses 2ml x 5.
Presentation
Zylexis for Horses is presented as a lyophilisate and solvent for suspension for intramuscular injection.
Each 2 ml dose contains inactivated Parapoxvirus ovis, strain D1701 that generates a minimum of 460 IFN Units *.
*: interferon units as determined in an in vitro stimulation assay in cattle lymphocytes.
Uses
Zylexis for Horses acts by stimulation of non-specific immune mechanisms and is of potential clinical value in the reduction of clinical signs of equine respiratory disease associated with stress/crowding.
In a field study, reduction of clinical signs (defined as the first time-point at which significant differences were evident between groups) was shown on day 5 after administration of the full treatment schedule and lasted less than a week.
Dosage and administration
For horses from 10 months of age.
Aseptically reconstitute the lyophilisate with the solvent provided. Shake well before use. The entire contents of the reconstituted vial should be administered intramuscularly as a single dose irrespective of body weight of the animal.
Dosage regimen
Three injections of a single dose for each animal are recommended.
The first two injections are administered with a 48-hour interval (day 0 and day 2) and the 3rd injection is administered on day 9.
To ensure efficacy of the treatment, it is important that the first dose of the product is administered shortly before or up to the day of crowding or exposure to other stressful conditions. It is important that the complete treatment schedule of 3 doses is administered.
Advice on correct administration
Sterile needles and syringes should be used for administration.
Syringes and needles should not have been sterilised chemically or be above ambient temperature. Do not use chemicals to disinfect or sterilise skin.
Shake well before use.
Aseptic precautions should be observed.
Reconstituted vaccine should be used immediately.
Contra-indications, warnings, etc
In a study in which horses of 4-10 months of age were administered Zylexis for Horses according to the recommended dosage regime, no systemic or local reactions were observed.
Special precautions for use in animals
The product should not be used for treatment of animals with chronic diseases with unclear causality.
No information is available to support the use of the authorised schedule in pregnant mares. One overdose (4 ml) was investigated in pregnant mares in the second half of pregnancy up to a few days before parturition.
No systemic or local reactions or negative effects were observed in these mares.
There is no information concerning safety in stallions.
No information is available on the safety and efficacy of this product when used with any other veterinary medicinal product. A decision to use this product before or after any other veterinary medicinal product therefore needs to be made on a case by case basis.
In an overdose (4 ml) safety study carried out in 1 day-old horses, no systemic or local reactions were observed.
Do not mix with any other veterinary medicinal product.
If you notice any serious effects or other effects not mentioned in this leaflet, please inform your veterinary surgeon.
All suspected adverse reactions and any suspected lack of efficacy should be reported to Zoetis UK Ltd technical helpline on 0845 300 8034.
Withdrawal period
Zero days.
User warnings
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
Pharmaceutical precautions
Store in a refrigerator (2°C – 8°C).
Protect from light.
Do not freeze.
Use immediately after reconstitution.
Do not use after the expiry date stated on the label.
Keep out of the reach and sight of children.
For animal treatment only.
Legal category
POM-V
Packaging Quantities
Boxes containing 5 glass vials of lyophilisate together with 5 glass vials of the solvent.
Shipping charges mainland GB zone1
Value | Weight | Delivery Charge |
Over £49.00 | Any Weight | FREE |
Under £49.00 | No weight limit | £4.50 |
Under £49.00 | Under 250 grams | £3.49 |
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Refrigerated Items
- Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
- Receipt Required: Someone must be available to receive the delivery. Woolcool packaging is designed for temperature-controlled goods, so parcels cannot be left unattended.
- Immediate Refrigeration: Upon receipt, refrigerate the contents immediately to ensure your food or medicine remains at the correct temperature.
- Failed Delivery Attempts: We are not responsible for the cost of replacements if a delivery attempt fails due to the absence of someone to receive it.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.