Semintra 4mg/ml Oral Solution for Cats.
Uses:
Reduction of proteinuria associated with chronic kidney disease (CKD) in cats.
Dosage and administration:
Oral use.
The recommended dose is 1 mg telmisartan/kg body weight (0.25 ml/kg body weight). The product is to be administered once daily directly into the mouth or with a small amount of food.
Semintra is an oral solution and is well accepted by most cats.
The solution should be given using the measuring syringe provided in the package. The syringe fits onto the bottle and has a kg-body weight scale.
After administration of the veterinary medicinal product close the bottle tightly with the cap, wash the measuring syringe with water and let it dry. To avoid contamination, use the provided syringe only to administer Semintra.
Contra-indications, warnings, etc:
Do not use during pregnancy or lactation. The safety of Semintra has not been established in breeding, pregnant or lactating cats.
Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Special precautions for use in animals:
The safety and efficacy of telmisartan has not been tested in cats under the age of 6 months. It is good clinical practice to monitor the blood pressure of cats receiving Semintra which are under anaesthesia.
Due to the mode of action of the veterinary medicinal product, transient hypotension may occur. Symptomatic treatment, e.g. fluid therapy, should be provided in case of any clinical signs of hypotension.
As known from substances acting on the Renin-Angiotensin-Aldosterone System (RAAS), a slight decrease in red blood cell count may occur. Red blood cell count should be monitored during therapy.
The following mild and transient gastrointestinal signs have rarely been observed in a clinical study (in order of decreasing frequency): mild and intermittent regurgitation, vomiting, diarrhoea or soft faeces.
Elevated liver enzymes have been very rarely observed and values normalised within a few days following cessation of therapy.
Effects attributable to the pharmacological activity of the product observed at the recommended treatment dose included reductions in blood pressure and decreases in red blood cell counts.
During concomitant therapy with amlodipine at the recommended dose no clinical evidence of hypotension was observed.
After administration of up to 5-fold of the recommended dose for 6 months, no adverse reactions were observed other than those mentioned above.
Administration of the product at overdose (up to 5-fold of the recommended dose for 6 months) resulted in marked reductions in blood pressure, decreases in red blood cell count (effects attributable to the pharmacological activity of the product) and increases in Blood Urea Nitrogen (BUN). These effects are unlikely to be observed under clinical conditions. However, in the event that transient hypotension does occur, symptomatic treatment, e.g. fluid therapy, should be provided.
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary products.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
Avoid eye contact. In case of accidental eye contact, rinse eyes with water. Wash hands after use.
Pregnant women should take special care to avoid contact with the product because substances acting on the RAAS, such as Angiotensin Receptor Blockers (ARBs) and ACE inhibitors (ACEi), have been found to affect the unborn child during pregnancy in humans.
People with hypersensitivity to telmisartan or other sartans/ARBs should avoid contact with the veterinary medicinal product.
Pharmaceutical precautions:
Shelf life of the veterinary medicinal product as packaged for sale (30 ml or 100 ml): 3 years.
Shelf life after first opening the immediate packaging: 6 months.
For animal treatment only. To be supplied only on veterinary prescription.
Keep out of the sight and reach of children.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements.
Legal category:
Legal category: POM-V
Packaging quantities:
Cardboard box containing one 45 ml HDPE bottle filled with 30 ml closed with a LDPE plug-in adapter and a tamper-proof child resistant closure and a measuring syringe. Cardboard box containing one 124 ml HDPE bottle filled with 100 ml closed with a LDPE plug-in adapter and a tamper-proof child resistant closure and a measuring syringe. Not all pack sizes may be marketed.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.
NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.
Estimated "Usually shipped in" information is shown against most products
Overseas orders
We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a legally valid signed and dated prescription.
Pick up
We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated Items
- Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
- Receipt Required: Someone must be available to receive the delivery. Woolcool packaging is designed for temperature-controlled goods, so parcels cannot be left unattended.
- Immediate Refrigeration: Upon receipt, refrigerate the contents immediately to ensure your food or medicine remains at the correct temperature.
- Failed Delivery Attempts: We are not responsible for the cost of replacements if a delivery attempt fails due to the absence of someone to receive it.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
