Protexin Pro-Enzorb is a supplement for dogs and cats which supports exocrine pancreatic function. It contains an active blend of three pancreatic enzymes - Lipase, Amylase and Protease, which are made into enterically-coated pellets which protect them from low pH levels in the stomach so they can reach the small intestine, where the digestive action is required.
The coated micro-pellets in Pro-Enzorb are not broken down
in the stomach, allowing them to reach the duodenum, where the digestive enzymes are released to aid food digestion.
Exocrine Pancreatic Insufficiency (EPI) is a syndrome caused
by insufficient synthesis and secretion of pancreatic enzymes.Maldigestion occurs when pancreatic enzyme activity is reduced. Undigested food components in the intestinal lumen result in diarrhoea, changes to the intestinal microflora and weight loss.
The main clinical signs associated
with EPI include:
• Weight loss
• Loose faeces – voluminous,
pale, malodorous
• Changes in appetite –
polyphagia, scavenging, coprophagia, pica
• Poor hair coat, flatulence, borborygmi
Common complications associated with EPI include a reduction
in serum cobalamin (Vitamin B12) and a dysbiosis of the
intestinal bacterial flora.
Cyanocobalamin
Cyanocobalamin (Vitamin B12) in the diet combines with
gastric or pancreatic intrinsic factor to aid absorption from
the intestinal tract into the bloodstream. 82% of dogs with
EPI are hypocobalaminemic due to a deficiency in production
of pancreatic intrinsic factor by acinar cells.
Veterinarians are advised to supplement parentally in all
cases presenting with hypocobalaminemia. Pro-Enzorb
contains high levels of cyanocobalamin to support the
maintenance of normocobalamin serum levels. Despite a
lack of pancreatic intrinsic factor, dogs with EPI are able to
complex oral cyanocobalamin with gastric intrinsic factor and
hyper-supplementation aids an intrinsic factor independent
absorption mechanism. High dose oral cobalamin supplementation has been shown to normalise serum levels
in hypocobalaminemic dogs with chronic enteropathies
Probiotics
Intestinal bacterial dysbiosis is common in animals with EPI not
only before enzyme replacement treatment has been started
but during treatment as well.
Intestinal dysbiosis occurs due to an increased presence of
undigested food in the intestinal lumen, a lack of bacteriostatic
factors in the pancreatic juice, and changes in intestinal motility and immune functions.
The supplementation of pancreatic enzymes does not affect the occurrence of intestinal dysbiosis and oral antibiotic therapy is often required to control the intestinal microflora. Probiotics aim to regulate the intestinal microflora and reduce the level of bacterial dysbiosis.
Directions for use:
DO NOT ADMINISTER CAPSULES WHOLE.
Capsules should be opened and the contents carefully mixed with food. The total daily amount should be divided equally between feeds. The dose may be adjusted to achieve normal faecal consistency and/or appropriate weight gain.
Note that the powder can be an irritant. It is advisable to wear gloves and wash hands after administration of the capsules.
Each capsule contains:
• 480mg Pancreatin enteric-coated micro-pellets
° Lipase – 27,050 Ph. Eur. U. (minimum)
° Amylase – 22,604 Ph. Eur. U. (minimum)
° Protease – 1,325 Ph. Eur. U. (minimum)
• Enterococcus faecium (NCIMB 10415) E1707 – 1 x 108 CFU
• Cyanocobalamin (Vitamin B12) – >1mg
Body weight* Number of capsules per day
<20kg 1 capsule
>20kg 2 capsules
Specification:
Additives:
Gut Flora Stabilisers
Protexin Probiotic
Enterrococcus faecium (DSM 10663/NCIMB 10415) 4b1707
2 x 1011 CFU/kg; 2 x 108 CFU/g
Nutritional Additives
Vitamin B12 (Cyanocobalamin)
Each capsule contains:
Lipase – 29,000 Ph. Eur. U. (minimum)
Amylase – 22,604 Ph. Eur. U. (minimum)
Protease – 1,450 Ph. Eur. U. (minimum)
Cyanocobalamin (Vitamin B12) – >1mg
Analytical Constituents:
Crude Protein 60%
Crude Fibre <0.1%
Oil 2%
Ash 11%
Acid insoluble ash 6%
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.
NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.
Estimated "Usually shipped in" information is shown against most products
Overseas orders
We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a legally valid signed and dated prescription.
Pick up
We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated Items
- Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
- Receipt Required: Someone must be available to receive the delivery. Woolcool packaging is designed for temperature-controlled goods, so parcels cannot be left unattended.
- Immediate Refrigeration: Upon receipt, refrigerate the contents immediately to ensure your food or medicine remains at the correct temperature.
- Failed Delivery Attempts: We are not responsible for the cost of replacements if a delivery attempt fails due to the absence of someone to receive it.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.
