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Nefotek 100mg/ml solution for injection 100ml

Nefotek

Item no: NEFOTEK
 
Prescription Medicine

Out of stock

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Clinical particulars
Target species
Cattle, pigs and horses
Indications for use
Cattle: Anti-inflammatory and analgesic treatment of diseases in the musculoskeletal system and the udder.
Pigs: Anti-inflammatory and antipyretic treatment of Postpartum Dysgalactia Syndrome –PDS - (Metritis Mastitis Agalactia Syndrome) and respiratory diseases.
Horses: Anti-inflammatory and analgesic treatment of diseases in the musculoskeletal system and joints.
Symptomatic analgesic treatment for colic. Postoperative pain and swelling.
Contraindications
Do not use in case of hypersensitivity to the active substance, or to any of the excipients.
Do not use in animals suffering from gastro-intestinal lesions, haemorrhagic diathesis, blood dyscrasia, impaired hepatic, cardiac or renal function.
Do not use in foals in their first month of life.
Do not use other non-steroidal anti-inflammatory drugs (NSAIDs) concurrently or within 24 hours of each other.
Special warnings for each target species
None
Special precautions for use in animals
Use in animals less than 6 weeks of age or in aged animals may involve additional risk. If such use cannot be avoided, animals may require a reduced dosage and careful management.
Avoid intra-arterial injection. Do not exceed the stated dose or duration of treatment.
Use with caution in dehydrated, hypovolemic or hypotensive animals as there is a potential risk of increased renal toxicity.. In the case of colic a supplementary dose may only be given after a thorough clinical examination.
Sufficient drinking water must be supplied at all times during treatment.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Take care to avoid accidental self injection.
In case of accidental self-injection, seek medical advice immediately and show the package leaflet or the label to the physician.
People with known hypersensitivity to ketoprofen or benzyl alcohol should avoid contact with the veterinary medicinal product.
Avoid splashes on the skin and eyes. Rinse thoroughly with water should this occur. If irritation persists seek medical advice.
Wash hands after use.
Adverse reactions (frequency and seriousness)
In very rare cases (less than 1 animal in 10,000 animals, including isolated reports) these signs can be observed:
· temporary irritation after repeated intramuscular injections
· gastric and intestinal irritation or ulceration (due to ketoprofen mechanism of action including inhibition of prostaglandin synthesis)
· reversible inappetence after repeated administration to swine
· allergic reactions
Use during pregnancy and lactation
The safety of ketoprofen has been investigated in pregnant laboratory animals, (rats, mice and rabbits) and in cattle, and showed no teratogenic or embryotoxic effects. The product may be given to pregnant and to lactating cattle, and to lactating sows.
As the effect of ketoprofen on the fertility, pregnancy or foetal health of horses have not been determined, the product should not be administered to pregnant horses.
As the safety of ketoprofen has not been assessed in pregnant sows, the product should be used in these case according to the benefit/risk assessment by the responsible veterinarian.
Interaction with other medicinal products and other forms of interaction
The veterinary medicinal product must not be administered in conjunction with, or within 24 hours of administration of other NSAIDs and glucocorticoids. Concurrent administration of diuretics, nephrotoxic drugs and anticoagulative drugs should be avoided.
Ketoprofen is highly bound to plasma proteins, and may displace or be displaced by other highly protein bound medicines, such as anticoagulants. Due to the fact that ketoprofen may inhibit platelet aggregation and cause gastrointestinal ulceration, it should not be used with other medicines that have the same profile of adverse drug reactions.
Amounts to be administered and administration route
Cattle: Intramuscular use or Intravenous use
3 mg ketoprofen/kg b.w/day (equivalent to 3 ml of the product /100 kg b.w/day) for up to 3 days.
Pigs: Intramuscular use
3 mg ketoprofen/kg b.w./day (equivalent to 3 ml of the product /100 kg b.w./day)administered once.
Horses: Intravenous use
2.2 mg ketoprofen/kg b.w./day (equivalent to 1 ml of the product /45 kg b.w./day) for 3 to 5 days. In the case of colic, treatment should not be repeated until a clinical re-examination has been carried out.
Not more than 5 ml should be administered at one intramuscular injection site.
The stoppers must not be punctured more than 166 times.
Overdose (symptoms, emergency procedures, antidotes)
No clinical signs were observed when the product was administered to horses at 5 times (11 mg/kg) the recommended dose for 15 days, to cattle at 5 times (15mg/kg/day) the recommended dose for 5 days, or to pigs at 3 times (9mg/kg/day) the recommended dose for 3 days.
Ketoprofen can lead to hypersensitivity reactions and moreover might have a detrimental effect on the gastric mucosa. This may require cessation of ketoprofen treatment and introduction of symptomatic therapy.
Withdrawal periods
Cattle, horses, pigs:
Meat and offal: 4 days
Milk (bovine): Zero hours
Not authorised for use in mares producing milk for human consumption.
Pharmaceutical particulars
Excipients
L Arginine
Benzyl alcohol (E1519)
Citric acid monohydrate (for pH adjustment)
Water for injection
Incompatibilities
In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other veterinary medicinal products.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 2 years.
Shelf life after first opening the immediate packaging: 28 days.
Special precautions for storage
Keep the container in the outer carton. Protect from light.
Do not refrigerate or freeze.
Nature and composition of immediate packaging
The product is packaged in amber type II glass vials of 100 ml and 250 ml.
The vials are closed with a type I rubber bromobutyl stopper oversealed with an aluminium cap. Vials are packaged in cardboard boxes containing 1unit.
Not all pack sizes may be marketed.
Disposal
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

 

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.

Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout. 

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

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We no longer send goods outside of the UK.

Prescription Items

Prescription items will be sent on receipt of a legally valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

  • Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
Wool cool keeps pharmaceutical products at fridge-like, ambient, or even freezing temperatures for up to 72 hours, and possibly longer depending on the contents and use of ice packs.
Important Delivery Information:
  • Receipt Required: Someone must be available to receive the delivery. Woolcool packaging is designed for temperature-controlled goods, so parcels cannot be left unattended.
  • Immediate Refrigeration: Upon receipt, refrigerate the contents immediately to ensure your food or medicine remains at the correct temperature.
  • Failed Delivery Attempts: We are not responsible for the cost of replacements if a delivery attempt fails due to the absence of someone to receive it.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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