Metacam 20 mg/ml Solution for Injection for Cattle, Pigs & Horses

Metacam 20 mg/ml Solution for Injection for Cattle, Pigs and Horses.

Presentation

One ml of the solution for injection contains 20 mg meloxicam and 150 mg ethanol (as preservative).

Uses

Metacam 20 mg/ml solution is a non-steroidal anti-inflammatory drug (NSAID) for use in cattle, pigs and horses.

Cattle

For use in acute respiratory infection with appropriate antibiotic therapy to reduce clinical signs in cattle.

For use in diarrhoea, in combination with oral rehydration therapy, to reduce clinical signs in calves of over one week of age and young non-lactating cattle.

For adjunctive therapy in the treatment of acute mastitis, in combination with antibiotic therapy.

For the relief of post-operative pain following dehorning in calves.

Pigs

For use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation.

For adjunctive therapy in the treatment of puerperal septicaemia and toxaemia (mastitis-metritis-agalactia syndrome) with appropriate antibiotic therapy.

Horses

For use in the alleviation of inflammation and relief of pain in both acute and chronic musculo-skeletal disorders.

For the relief of pain associated with equine colic

Dosage and administration

Cattle: Single subcutaneous or intravenous injection at a dose rate of 0.5 mg meloxicam/kg bodyweight (i.e. 2.5 ml/100 kg bodyweight) in combination with antibiotic therapy or with oral rehydration therapy as appropriate.

Pigs: Single intramuscular injection at a dosage of 0.4 mg meloxicam/kg bodyweight (i.e. 2.0ml/100kg bodyweight) in combination with antibiotic therapy, as appropriate. If required, a second administration of meloxicam can be given after 24 hours.

Horses: Single intravenous injection at a dosage of 0.6 mg meloxicam/kg bodyweight (i.e. 3.0ml/100kg bodyweight). Metacam 15mg/ml oral suspension may be used for the continuation of treatment at a dosage of 0.6 mg meloxicam/kg bodyweight, 24 hours after administration of the injection.

Contra-indications, warnings, etc

Do not use in horses less than 6 weeks of age.

Do not use in animals suffering from impaired hepatic, cardiac or renal function and haemorrhagic disorders, or where there is evidence of ulcerogenic gastrointestinal lesions.

Do not use in pregnant or lactating mares.

Not authorised to use in horses producing milk for human consumption.

Do not use in case of hypersensitivity to the active substance or to any of the excipients.

For the treatment of diarrhoea, do not use in animals less than one week of age.

Treatment of calves with Metacam 20 minutes before dehorning reduces post-operative pain. Metacam alone will not provide adequate pain relief during the dehorning procedure. To obtain adequate pain relief during surgery co-medication with an appropriate analgesic is needed.

If adverse reactions occur, treatment should be discontinued and the advice of a veterinarian should be sought.

Avoid use in very severely dehydrated, hypovolaemic or hypotensive animals which require parenteral rehydration, as there may be a potential risk of renal toxicity.

In case of inadequate relief of pain when used in the treatment of equine colic, careful re-evaluation of the diagnosis should be made as this could indicate the need for surgical intervention.

In cattle and pigs, subcutaneous, intramuscular as well as intravenous administration is well tolerated; only a slight transient swelling at the injection site following subcutaneous administration was observed in less than 10 % of the cattle treated in clinical studies.

In horses, a transient swelling at the injection site can occur but resolves without intervention.

In very rare cases anaphylactoid reactions, which may be serious (including fatal), may occur and should be treated symptomatically.

Do not administer concurrently with glucocorticosteroids, other non-steroidal anti-inflammatory drugs or with anti-coagulant agents.

In case of overdose, symptomatic treatment should be initiated.

Operator warnings

Accidental self-injection may give rise to pain. People with known hypersensitivity to NSAIDs should avoid contact with the veterinary medicinal product.

In case of accidental self-injection, seek medical advice immediately and show the package insert or label to the physician.

Disposal Advice

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

For animal treatment only.

Keep out of reach and sight of children.

Withdrawal Period

Cattle:

Meat and offal – 15 days.

Milk – 120 hours.

Pigs:

Meat and offal – 5 days.

Horses:

Meat and offal - 5 days.

Pharmaceutical precautions

Shelf life of broached vial: 28 days

Do not use after the expiry date stated on the carton and on the bottle.

Avoid introduction of contamination during use.

Legal category

POM-V

Packaging Quantities

Cardboard box with 1 colourless glass injection vial each containing 50 ml, 100 ml or 250 ml.

Cardboard box with 12 colourless glass injection vials each containing 100 ml.

Cardboard box with 6 colourless glass injection vials each containing 250 ml.

Each vial is closed with a rubber stopper and sealed with an aluminium cap.