Species:Ornamental birds, Rabbits, Reptiles, Small mammals. Active ingredient:Enrofloxacin.
1 ml contains as active substance:
Enrofloxacin25 mg
Excipient(s): Benzyl alcohol (E-1519)18 mg
Target species
Pet rabbits, rodents, ornamental birds and reptiles.
Indications for use, specifying the target species
Pet rabbits
Treatment of infections of the digestive and respiratory tracts caused by enrofloxacin susceptible strains of: Escherichia coli, Pasteurella multocida and Staphylococcus spp.
Treatment of skin and wound infections caused by enrofloxacin susceptible strains of Staphylococcus aureus.
Rodents, reptiles and ornamental birds
Treatment of infections of the digestive and respiratory tracts where clinical experience, if possible, supported by susceptibility testing of the causal organism, indicates enrofloxacin as the substance of choice.
Contraindications
Do not use in case of known hypersensitivity to fluoroquinolones or to any of the excipients.
Do not use in animals that are epileptic or suffer from seizures since enrofloxacin may cause CNS stimulation.
Do not use in animals producing food for human consumption.
Special warnings for each target species
None.
Special precautions for use
Special precautions for use in animals
Official and local antimicrobial policies should be taken into account when the product is used. Fluoroquinolones should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials. Whenever possible, fluoroquinolones should only be used based on susceptibility testing.
Use of the product deviating from instructions given in the SPC may increase the prevalence of bacteria resistant to fluoroquinolones and may decrease the effectiveness of treatment with other quinolones due to the potential for cross resistance.
Special caution should be taken when using enrofloxacin in animals with impaired renal function.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
People with known hypersensitivity to fluoroquinolones should avoid any contact with the product.
Personal protective equipment consisting of impermeable gloves should be worn when handling the veterinary medicinal product.
Avoid skin and eye contact. Wash any splashes from skin or eyes immediately with water.
Wash hands after use. Do not eat, drink or smoke whilst handling the product.
Adverse reactions (frequency and seriousness)
Digestive tract disorders (e.g. diarrhoea) may occur in very rare cases. These signs are generally mild and transient.
During the period of rapid growth, enrofloxacin may affect articular cartilage.
Use during pregnancy, lactation or lay
Pet rabbits and rodents
Laboratory studies in rats and rabbits have not produced any evidence of teratogenic effects but have shown evidence of foetotoxic effects at maternotoxic doses. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Use only accordingly to the benefit/risk assessment by the responsible veterinarian.
Birds and reptiles
The safety of the veterinary medicinal product has not been established during lay, although detrimental effects on developing eggs of avian scavengers have been reported when these birds ingest livestock meat from animals previously administered fluoroquinolones. Use only accordingly to the benefit-risk assessment by the responsible veterinarian.
Interaction with other medicinal products and other forms of interaction
Do not use enrofloxacin concomitantly with antimicrobial substances acting antagonistically to quinolones (e.g. macrolides, tetracyclines or phenicols).
Do not use concurrently with theophylline as the elimination of theophylline may be delayed.
The simultaneous application of substances containing aluminium or magnesium can impair the absorption of enrofloxacin
Amounts to be administered and administration route
Instructions for use
For administration by oral gavage.
The undiluted veterinary medicinal product is strongly alkaline and, therefore, to avoid caustic effects, it is essential to dilute the product with at least 4 parts water prior to administration. In the case of smaller animals (weighing less than 500 g), it may be appropriate to dilute 0.1 ml of the neat product with greater than 4 parts water and administer a proportion of the total volume.
10 ml bottle: A 1 ml syringe is provided with the 10 ml bottle for withdrawal of small volumes of the product and to facilitate dilution prior to administration. This syringe has dosage graduations of 0.01 and 0.1 ml. The lowest volume that has been demonstrated to be accurate is 0.1 ml. Therefore, for accuracy of dosing, it is recommended to draw up a minimum of 0.1 ml of product.
The diluted solution should be mixed thoroughly prior to administration.
The dilution should be made on a twice-daily basis immediately prior to provision, preferably in a glass container. Any unused solution should be disposed of immediately after use.
After extracting and expressing the amount of product required the syringes should be washed with lukewarm water to remove any remaining product. The syringe can subsequently be used to prepare another solution or be opened, emptied and left to dry.
Dosage
Owing to physiological and pharmacokinetic differences between the wide range of species for which this product is indicated, the dose rates below are for guidance only. Depending upon the species of animal and the infection to be treated, alternative doses may be appropriate using an evidence-based approach. However, any change in dosing regimen should be based on a benefit:risk assessment by the responsible veterinarian, as tolerance at higher doses has not been investigated.
To avoid inhalation of the medication, care should be taken with restraint of the animal and administration of the product.
Rodents and pet rabbits
5 mg enrofloxacin per kg bodyweight (0.2 ml per kg bodyweight), twice daily for 7 days.
Reptiles
5 mg enrofloxacin per kg bodyweight (0.2 ml per kg bodyweight), at 24-48 hour intervals for 6 days.
Reptiles are ectothermic, relying on external heat sources to maintain their body temperature at the optimum level for correct function of all body systems. Metabolism of substances and activity of the immune system are, thus, critically dependant on the body temperature. Therefore, the veterinarian must be aware of correct temperature requirements of the respective reptile species and the hydration status of the individual patient. Furthermore, it has to be considered that large differences exist in the pharmacokinetic behaviour of enrofloxacin among different species, which additionally will influence the decision about the correct dosage of the veterinary medicinal product. Therefore, the recommendations made here can only be used as a starting point for individual dose setting.
Ornamental birds
10 mg enrofloxacin per kg bodyweight (0.4 ml per kg bodyweight), twice daily 7 days.
Overdose (symptoms, emergency procedures, antidotes), if necessary
In cases of accidental overdose digestive tract disorders (e.g. vomiting, diarrhoea) and neurological disorders may occur.
Withdrawal period
Do not use in animals producing food intended for human consumption.
Species:Ornamental birds, Rabbits, Reptiles, Small mammals. Active ingredient:Enrofloxacin.
1 ml contains as active substance:
Enrofloxacin25 mg
Excipient(s): Benzyl alcohol (E-1519)18 mg
Target species
Pet rabbits, rodents, ornamental birds and reptiles.
Indications for use, specifying the target species
Pet rabbits
Treatment of infections of the digestive and respiratory tracts caused by enrofloxacin susceptible strains of: Escherichia coli, Pasteurella multocida and Staphylococcus spp.
Treatment of skin and wound infections caused by enrofloxacin susceptible strains of Staphylococcus aureus.
Rodents, reptiles and ornamental birds
Treatment of infections of the digestive and respiratory tracts where clinical experience, if possible, supported by susceptibility testing of the causal organism, indicates enrofloxacin as the substance of choice.
Contraindications
Do not use in case of known hypersensitivity to fluoroquinolones or to any of the excipients.
Do not use in animals that are epileptic or suffer from seizures since enrofloxacin may cause CNS stimulation.
Do not use in animals producing food for human consumption.
Special warnings for each target species
None.
Special precautions for use
Special precautions for use in animals
Official and local antimicrobial policies should be taken into account when the product is used. Fluoroquinolones should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials. Whenever possible, fluoroquinolones should only be used based on susceptibility testing.
Use of the product deviating from instructions given in the SPC may increase the prevalence of bacteria resistant to fluoroquinolones and may decrease the effectiveness of treatment with other quinolones due to the potential for cross resistance.
Special caution should be taken when using enrofloxacin in animals with impaired renal function.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
People with known hypersensitivity to fluoroquinolones should avoid any contact with the product.
Personal protective equipment consisting of impermeable gloves should be worn when handling the veterinary medicinal product.
Avoid skin and eye contact. Wash any splashes from skin or eyes immediately with water.
Wash hands after use. Do not eat, drink or smoke whilst handling the product.
Adverse reactions (frequency and seriousness)
Digestive tract disorders (e.g. diarrhoea) may occur in very rare cases. These signs are generally mild and transient.
During the period of rapid growth, enrofloxacin may affect articular cartilage.
Use during pregnancy, lactation or lay
Pet rabbits and rodents
Laboratory studies in rats and rabbits have not produced any evidence of teratogenic effects but have shown evidence of foetotoxic effects at maternotoxic doses. The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Use only accordingly to the benefit/risk assessment by the responsible veterinarian.
Birds and reptiles
The safety of the veterinary medicinal product has not been established during lay, although detrimental effects on developing eggs of avian scavengers have been reported when these birds ingest livestock meat from animals previously administered fluoroquinolones. Use only accordingly to the benefit-risk assessment by the responsible veterinarian.
Interaction with other medicinal products and other forms of interaction
Do not use enrofloxacin concomitantly with antimicrobial substances acting antagonistically to quinolones (e.g. macrolides, tetracyclines or phenicols).
Do not use concurrently with theophylline as the elimination of theophylline may be delayed.
The simultaneous application of substances containing aluminium or magnesium can impair the absorption of enrofloxacin
Amounts to be administered and administration route
Instructions for use
For administration by oral gavage.
The undiluted veterinary medicinal product is strongly alkaline and, therefore, to avoid caustic effects, it is essential to dilute the product with at least 4 parts water prior to administration. In the case of smaller animals (weighing less than 500 g), it may be appropriate to dilute 0.1 ml of the neat product with greater than 4 parts water and administer a proportion of the total volume.
10 ml bottle: A 1 ml syringe is provided with the 10 ml bottle for withdrawal of small volumes of the product and to facilitate dilution prior to administration. This syringe has dosage graduations of 0.01 and 0.1 ml. The lowest volume that has been demonstrated to be accurate is 0.1 ml. Therefore, for accuracy of dosing, it is recommended to draw up a minimum of 0.1 ml of product.
The diluted solution should be mixed thoroughly prior to administration.
The dilution should be made on a twice-daily basis immediately prior to provision, preferably in a glass container. Any unused solution should be disposed of immediately after use.
After extracting and expressing the amount of product required the syringes should be washed with lukewarm water to remove any remaining product. The syringe can subsequently be used to prepare another solution or be opened, emptied and left to dry.
Dosage
Owing to physiological and pharmacokinetic differences between the wide range of species for which this product is indicated, the dose rates below are for guidance only. Depending upon the species of animal and the infection to be treated, alternative doses may be appropriate using an evidence-based approach. However, any change in dosing regimen should be based on a benefit:risk assessment by the responsible veterinarian, as tolerance at higher doses has not been investigated.
To avoid inhalation of the medication, care should be taken with restraint of the animal and administration of the product.
Rodents and pet rabbits
5 mg enrofloxacin per kg bodyweight (0.2 ml per kg bodyweight), twice daily for 7 days.
Reptiles
5 mg enrofloxacin per kg bodyweight (0.2 ml per kg bodyweight), at 24-48 hour intervals for 6 days.
Reptiles are ectothermic, relying on external heat sources to maintain their body temperature at the optimum level for correct function of all body systems. Metabolism of substances and activity of the immune system are, thus, critically dependant on the body temperature. Therefore, the veterinarian must be aware of correct temperature requirements of the respective reptile species and the hydration status of the individual patient. Furthermore, it has to be considered that large differences exist in the pharmacokinetic behaviour of enrofloxacin among different species, which additionally will influence the decision about the correct dosage of the veterinary medicinal product. Therefore, the recommendations made here can only be used as a starting point for individual dose setting.
Ornamental birds
10 mg enrofloxacin per kg bodyweight (0.4 ml per kg bodyweight), twice daily 7 days.
Overdose (symptoms, emergency procedures, antidotes), if necessary
In cases of accidental overdose digestive tract disorders (e.g. vomiting, diarrhoea) and neurological disorders may occur.
Withdrawal period
Do not use in animals producing food intended for human consumption.
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.
Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout.
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Estimated "Usually shipped in" information is shown against most products
Overseas orders
We no longer send goods outside of the UK.
Prescription Items
Prescription items will be sent on receipt of a legally valid signed and dated prescription.
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We offer a pickup service for orders placed over the phone.
Please ring us on 01833 641112 for more information.
Refrigerated Items
- Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
- Receipt Required: Someone must be available to receive the delivery. Woolcool packaging is designed for temperature-controlled goods, so parcels cannot be left unattended.
- Immediate Refrigeration: Upon receipt, refrigerate the contents immediately to ensure your food or medicine remains at the correct temperature.
- Failed Delivery Attempts: We are not responsible for the cost of replacements if a delivery attempt fails due to the absence of someone to receive it.
We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.
*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.