Qualitative and quantitative composition.
Active substance: Chlortetracycline HCl 2.45% w/w
Excipients:
Patent Blue V, colouring agent 0.15% w/w
Butane 100 68.77% w/w
For a full list of excipients, see Excipients.
Pharmaceutical form
Cutaneous spray, suspension. Blue coloured.
Clinical particulars
Target species
Cattle, sheep and pigs.
Indications for use
Prevention of infections of superficial traumatic or surgical wounds caused by micro-organisms sensitive to chlortetracycline.
The product can be used as part of a treatment for superficial claw/hoof infections, in particular interdigital dermatitis (foot rot) in sheep and digital dermatitis in cattle.
Contraindications
Do not use in case of hypersensitivity to tetracyclines.
Special precautions for use in animals
Protect the eyes when spraying in the vicinity of the head. Clean the affected area thoroughly before spraying. Treatment of foot conditions should always be preceded by appropriate paring of the hoof, as this is critical for achieving an adequate response. After spraying the feet, the animal should be kept on dry ground for at least one hour.
The animal should be discouraged from licking the treated area, or treated areas on other animals.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Direct contact with the skin should be avoided because of sensitisation, contact dermatitis and possible hypersensitivity reactions to chlortetracycline. Wear appropriate impermeable gloves whilst handling the product.
Because of risk of eye irritation, contact with the eyes should be avoided. Protect the eyes and face.
Do not spray on a naked flame or any incandescent material. Do not pierce or burn the container, even after use.
Avoid inhaling vapours. Apply the product in open air or in sufficiently ventilated area.
Wash hands after use. Do not eat or smoke whilst administering the product.
In case of accidental ingestion or in case of contact with eyes, seek medical advice immediately and show the label to the physician.
Adverse reactions
Hypersensitivity reactions may occur rarely.
Use during pregnancy and lactation
Following cutaneous administration of Cyclo spray, absorption of chlortetracycline is negligible and it is not detectable in the milk.
Interactions
After cutaneous administration of chlortetracycline spray, absorption of chlortetracycline is negligible. No data on interactions with other local treatments are available.
Amounts to be administered and administration route
Cyclo spray is indicated for cutaneous administration. Shake the container thoroughly before spraying. The container should be held at a distance of 15-20 cm from the area to be sprayed; spray for approximately 3 seconds (equivalent to approximately 3.9 g of product or 0.10 g chlortetracycline) until the treatment area is evenly coloured. In case of claw/hoof infections this treatment should be repeated after 30 seconds.
- For prevention of infections after superficial traumatic or surgical wounds a single administration is recommended.
- For treatment of dermatitis digitalis, a double administration (with a 30 second interval) is recommended daily for three consecutive days.
- For treatment of other hoof infections (foot rot), a double administration (with a 30 second interval) is recommended. Dependent on the seriousness of the injury and the rate of improvement treatment should be repeated within 1 to 3 days.
Overdose
Not applicable.
Withdrawal period
Meat: zero days; Milk: zero hours. Do not use on the udder of lactating animals if milk is intended for human consumption.
Stained part of the pigskin must be removed prior to the rest of the animal being used for human consumption.
Pharmacological particulars
Pharmacodynamic properties
Chlortetracycline belongs to the pharmacotherapeutic group of tetracycline antibiotics.
ATC Vet code: QD06AA02
In vitro, chlortetracycline is primarily bacteriostatic. Chlortetracycline exerts its action by inhibiting the protein synthesis of the bacterial cell. Especially cell-division and the formation of the cell wall are impaired. Chlortetracycline binds to receptors on the 30S-subunit of the bacterial ribosome where they interfere with the binding of the aminoacyl-transfer RNA to the acceptor site on the messenger RNA ribosome complex.
Pharmacokinetic properties
Following cutaneous administration of chlortetracycline spray, chlortetracycline absorption is negligible. Therefore Cyclo spray will only have a local effect, no systemic effects are to be anticipated.
Pharmaceutical particulars
Excipients
Patent Blue V [E131], butane (Butan 100), colloidal anhydrous silica (Aerosil 200), isopropyl alcohol, sorbitan trioleate (Span 85).
Incompatibilities
None known.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Special precautions for storage
Pressurised container. Do not expose the container to direct sunlight or to temperatures higher than 50C. Keep away from sources of ignition. Keep out of the reach and sight of children.
Immediate packaging
270 ml or 520 ml pressurised container of coated tin plate with a plastic valve mechanism and spraying nozzle. Not all pack sizes may be marketed.
Disposal
Shipping charges mainland GB zone1
| Value | Weight | Delivery Charge |
| Over £49.00 | Any Weight | FREE |
| Under £49.00 | No weight limit | £4.50 |
| Under £49.00 | Under 250 grams | £3.49 |
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We no longer send goods outside of the UK.
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Prescription items will be sent on receipt of a legally valid signed and dated prescription.
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Please ring us on 01833 641112 for more information.
Refrigerated Items
- Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
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*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.