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Clinacin Tablets

Chanelle

Item no: CLINACIN
 
Prescription Medicine
Option
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  • 25mg (pack of 100)
  • 300mg (pack of 100)
Max 1 per customer
£26.09 - £94.95
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Presentation
Clomicalm is available in divisible, flavoured tablets of 3 dosage strengths:
Clomicalm 5mg Clomipramine hydrochloride 5.00mg
Clomicalm 20mg Clomipramine hydrochloride 20.00mg
Clomicalm 80mg Clomipramine hydrochloride 80.00mg

Uses
As an aid in the treatment of separation-related disorders in dogs manifested by destruction and inappropriate elimination (defecation and urination) and only in combination with behavioural modification techniques.

Dosage and administration
Dosage: Clomicalm is administered twice daily at a dose of 1-2mg/kg to give a total daily dose of 2-4mg/kg according to the following table:
Dosage per administration
Bodyweight Clomicalm 5mg Clomicalm 20mg Clomicalm 80mg
1.25-2.5kg
>2.5-5kg 0.5 tablet
1 tablet
>5-10kg
>10-20kg 0.5 tablet
1 tablet
>20-40kg
>40-80kg 0.5 tablet
1 tablet

Administration: Clomicalm is given orally with or without food. In clinical trials, a treatment time of 2-3 months with Clomicalm in combination with behavioural modification techniques was sufficient to control the symptoms of separation-related disorders. Some cases may require longer treatment. In cases showing no improvement after 2 months, treatment with Clomicalm should be ceased.

Contra-indications, warnings, etc
Contra-indications:
Known hypersensitivity to clomipramine and related tricyclic antidepressants. Male breeding dogs.
Warnings:
Clomicalm may cause sporadic vomiting, changes in appetite or lethargy. Vomiting may be reduced by co-administration with a small quantity of food.
Special precautions for use:
Dog: It is recommended to administer Clomicalm to dogs with cardiovascular dysfunction or epilepsy with caution and only after an assessment of the benefit/risk ratio. Because of its potential anticholinergic properties, Clomicalm should also be used with care in dogs with narrow angle glaucoma, reduced gastrointestinal motility or urinary retention. Clomicalm should be used under veterinary supervision. The efficacy and safety of Clomicalm has not been established in dogs weighing less than 1.25kg or under 6 months of age.
Persons administering the product: In children, accidental ingestion should be regarded as serious. There is no specific antidote. In case of accidental ingestion, seek medical advice immediately and show the product label. Overdose in human beings causes anticholinergic effect although central nervous and cardiovascular systems may also be affected. People with known hypersensitivity to clomipramine should administer the product with caution.
Use during pregnancy and lactation: The safety of Clomicalm has not been established in female dogs during pregnancy and lactation. There was evidence of embryotoxic effects of clomipramine in laboratory animal studies.
Interaction with other medicaments: Recommendations on the interaction between Clomicalm and other medicaments are derived from studies in species other than dogs. Clomicalm may potentiate the effects of the anti-arrhythmic drug quinidine, anticholinergic agents (e.g. atropine), other CNS active drugs (e.g. barbiturates, benzodiazepines, general anaesthetics, neuroleptics), sympathomimetics (e.g. adrenaline) and coumarine derivatives. It is recommended not to administer Clomicalm in combination with, or within 2 weeks of therapy with, monoamine oxidase inhibitors. Simultaneous administration with cimetidine may lead to increased plasma levels of clomipramine. Plasma levels of certain anti-epileptic drugs, such as phenytoin and carbamazepine, may be increased by coadministration with Clomicalm.
Overdose: At overdose with 20mg/kg Clomicalm (5 times the maximum therapeutic dose), bradycardia and arrhythmias (atrioventricular node block and ventricular escape beats) were observed approximately 12 hours after dosing. Overdose with 40mg/kg (20 times the recommended dose) of Clomicalm produced hunched posture, tremors, flushed abdomen and decreased activity in dogs. Higher doses (500mg/kg i.e. 250 times the recommended dose) produced emesis, defecation, drooped eyes, trembling and quietness. Still higher doses (725mg/kg) produced, in addition, convulsions and death.
Environmental precautions: Any unused product or waste material should be disposed of in accordance with local requirements.

Pharmaceutical precautions
Store below 30C in a dry place. Sensitive to moisture. Store unused product in the original container. For animal treatment only. Keep out of reach of children

Legal category
POM-V (previously POM

Packaging Quantities
Each tablet size is supplied in plastic bottles containing 30 tablets (with desiccant).

Further information
Nil.

Marketing authorisation numbers
Clomicalm 5mg - EU/2/98/007/001
Clomicalm 20mg - EU/2/98/007/002
Clomicalm 80mg - EU/2/98/007/003

 

Shipping charges mainland GB zone1

Value Weight Delivery Charge
Over £49.00 Any Weight FREE
Under £49.00 No weight limit £4.50
Under £49.00 Under 250 grams £3.49

Most orders are despatched the same day and standard delivery is 3 to 5 working days from despatch. FAST Expedited options are available at extra cost - these usually arrive in 24-48hrs from dispatch but delays are possible during busy periods.

Postcodes outside of Zone 1 (including some areas within mainland UK) may incur extra carriage charges due to surcharges imposed by the couriers. These will be calculated on the website at the checkout. 

NB: Orders placed with faster delivery must be placed before 13:00 to ensure same day dispatch (excluding weekends and bank holidays). Please also check on the product page that the items ordered show 'In Stock' otherwise your order will be delayed until the stock becomes available, which in most cases will only be 24hrs.

Estimated "Usually shipped in" information is shown against most products

Overseas orders

We no longer send goods outside of the UK.

Prescription Items

Prescription items will be sent on receipt of a legally valid signed and dated prescription.

Pick up

We offer a pickup service for orders placed over the phone.

Please ring us on 01833 641112 for more information.

Refrigerated Items

  • Refrigerated lines Packaging Cost: Despatched with Woolcool Refrigerated Packaging for £7.50.
Wool cool keeps pharmaceutical products at fridge-like, ambient, or even freezing temperatures for up to 72 hours, and possibly longer depending on the contents and use of ice packs.
Important Delivery Information:
  • Receipt Required: Someone must be available to receive the delivery. Woolcool packaging is designed for temperature-controlled goods, so parcels cannot be left unattended.
  • Immediate Refrigeration: Upon receipt, refrigerate the contents immediately to ensure your food or medicine remains at the correct temperature.
  • Failed Delivery Attempts: We are not responsible for the cost of replacements if a delivery attempt fails due to the absence of someone to receive it.

We want you to be completely satisfied with any purchase. If not any item* can be returned to us within 14 days of receipt for exchange or refund Please give us a ring for a returns number on 01833 641112 or alternatively email sales@hyperdrug.co.uk to obtain a returns number.

*Due to legal requirements medicines may not be returned except to correct an error in despatch or in response to an "official recall". If an item is believed to be faulty it should be returned for inspection and it may be necessary to forward it to the manufacturers for testing before replacements or refunds can be authorised. This does not infringe legal rights. Please contact our customer services for a "Returns Number" which must appear on the outside of the package or it will not be accepted. We advise customers to use an insured method of shipping and to retain proof of despatch. We may refuse returns on products specially obtained or manufactured to order. Items must be returned unsoiled and unused and sent adequately packed and carriage paid.

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